Who is sponsoring NCT05936996?

NCT05936996 is sponsored by Essential Medical, Inc..

What drugs are being tested in NCT05936996?

Interventions in NCT05936996: MANTA Vascular Closure Device.

What condition does NCT05936996 study?

NCT05936996 studies Femoral Arteriotomy Closure.

Is NCT05936996 still recruiting?

NCT05936996 is currently completed. Last updated 12 November 2025.

Last reviewed 2025-11-12 · How we verify

NCT05936996: ACCESS MANTA

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Prospective Clinical Registry Evaluating Contemporary MANTA Outcomes

Completed Last updated 12 November 2025

What this trial tests

trial testing MANTA Vascular Closure Device in Femoral Arteriotomy Closure in 258 participants. Completed in 30 October 2025.

Timeline

15 November 2023

Primary endpoint
20 June 2025

30 October 2025

Quick facts

Lead sponsor	Essential Medical, Inc.
Status	Completed
Study type	OBSERVATIONAL
Enrollment	258
Start date	15 November 2023
Primary completion	20 June 2025
Estimated completion	30 October 2025
Sites	10 locations across Canada, United States

Drugs / interventions tested

MANTA Vascular Closure Device

Conditions studied

Femoral Arteriotomy Closure — all drugs for Femoral Arteriotomy Closure →

Sponsor

Essential Medical, Inc.

Who can join

21 and older, any sex, with Femoral Arteriotomy Closure. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is an observational study designed to evaluate the safety and clinical outcomes of the MANTA® Vascular Closure Device (VCD) (the MANTA® Device) in TAVR procedures. The study will enroll participants who are undergoing a TAVR procedure. The purpose of this study is to examine and collect data on outcomes of contemporary MANTA® large bore closure in standard of care (SOC) TAVR procedures with on-label use of the MANTA® device including appropriate patient selection and proper vascular access.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other trials of MANTA Vascular Closure Device

Trials testing the same drug.

NCT05142566 — MANTA Ultrasound Closure Study · NA · terminated

Other recruiting trials for Femoral Arteriotomy Closure

Currently open trials in the same condition.

NCT06851481 — The Ladera Suture-Mediated Large Bore Closure Study · NA · recruiting

Other Essential Medical, Inc. trials

Trials by the same sponsor.

NCT05142566 — MANTA Ultrasound Closure Study · NA · terminated
NCT03330002 — MANTA Registry for Vascular Large-bore Closure · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05936996 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Essential Medical, Inc.
Last refreshed: 12 November 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05936996.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing