Who is sponsoring NCT05936749?

NCT05936749 is sponsored by Istituto Clinico Humanitas.

What drugs are being tested in NCT05936749?

Interventions in NCT05936749: Pre-implantation genetic testing.

What condition does NCT05936749 study?

NCT05936749 studies Genetic Disease, Aneuploidy.

Is NCT05936749 still recruiting?

NCT05936749 is currently completed. Last updated 10 July 2023.

Last reviewed 2023-07-10 · How we verify

NCT05936749

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Pre-implantation Genetic Testing for Monogenic Disease: Single Center Experience

Completed Last updated 10 July 2023

What this trial tests

trial testing Pre-implantation genetic testing in Genetic Disease in 76 participants. Completed in 12 December 2022.

Timeline

2 January 2016

Primary endpoint
12 December 2022

12 December 2022

Quick facts

Lead sponsor	Istituto Clinico Humanitas
Status	Completed
Study type	OBSERVATIONAL
Enrollment	76
Start date	2 January 2016
Primary completion	12 December 2022
Estimated completion	12 December 2022

Drugs / interventions tested

Pre-implantation genetic testing

Conditions studied

Genetic Disease — all drugs for Genetic Disease →
Aneuploidy — all drugs for Aneuploidy →

Sponsor

Istituto Clinico Humanitas

Who can join

Adults 34 to 42, female only, with Genetic Disease or Aneuploidy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This monocentric retrospective observational study aims to evaluate the efficacy of pre-implantation genetic testing for monogenic diseases (PGT-M). The effectiveness will be assessed in terms of live birth rate (LBR), cumulative live birth rate (CLBR) per couple, and abortion rate (AR). Considering how many cycles the participants have undergone to achieve a viable blastocyst. The secondary objective is to evaluate the incidence of aneuploidy in unaffected embryos, in order to understand the need for pre-implantation genetic testing for aneuploidy (PGT-A)in addition to PGT-M.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Genetic Disease

Currently open trials in the same condition.

NCT06744543 — Clinical Decision Support to Identify Pediatric Patients With Undiagnosed Genetic Disease · NA · active not recruiting
NCT06435468 — Biocollection of Rare Pediatric-onset of Autoimmune and Autoinflammatory Diseases · NA · recruiting
NCT06821386 — N-Care Project: Enhancing Asian-Pacific Collaboration · recruiting
NCT07365254 — Accurate Assessment and Intervention Research on Newborn Whole Genome Sequencing and Genetic Disease Risk · recruiting
NCT06725901 — Pediatric Neurogenetic Diagnosis Support Platform · NA · recruiting

Other Istituto Clinico Humanitas trials

Trials by the same sponsor.

NCT06944288 — Microbiota as Early Diagnostic and predictivE Factor for Osteoarthritic Degeneration and Microbial Contamination · NA · not yet recruiting
NCT07358247 — Postoperative Outcomes of Single-stapled Anastomosis Combined With Transanal Natural Orifice Specimen Extraction · not yet recruiting
NCT07362342 — RIght VEntricle Response to Major Lung Resection in VATS and Robotic Surgery · not yet recruiting
NCT07346274 — Intra-operative Hypotension and Post-operative Lactate Level After Pancreatic-duodenectomy. · enrolling by invitation
NCT07491419 — The Impact of Fast Antimicrobial Sensitivity Testing Tools on Stewardship Antibiotic and Clinical Outcome (ACT-FAST) · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05936749 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Istituto Clinico Humanitas
Last refreshed: 10 July 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05936749.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing