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NCT05936437
Clinical Benefits and Safety of Combined Polynucleotides and Hyaluronic Acid - Newest - for Acne Scars Treatment
NA trial testing Subjects treated with Newest medical device in Atrophic Scar in 30 participants. Completed in 24 July 2025.
24 July 2025
Quick facts
| Lead sponsor | Mastelli S.r.l |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 16 November 2023 |
| Primary completion | 24 July 2025 |
| Estimated completion | 24 July 2025 |
| Sites | 1 location across Italy |
Drugs / interventions tested
- Subjects treated with Newest medical device
Conditions studied
- Atrophic Scar — all drugs for Atrophic Scar →
Sponsor
Mastelli S.r.l
Who can join
Adults 20 to 60, any sex, with Atrophic Scar. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This clinical study wants to evaluate the efficacy and safety of a medical device combining "Polynucleotide Highly Purified Technology" (PN-HPT™) and hyaluronic acid (Newest-Mastelli S.r.l) for treating moderate-to-severe atrophic post-acne scars.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05936437
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Mastelli S.r.l trials
Trials by the same sponsor.
- NCT07185191 — Evaluation of the Safety and Performance of the Medical Device RDM36 in the Treatment of Periodontal Gingival Contractio · NA · not yet recruiting
- NCT07151859 — Clinical Investigation on a Polynucleotide-based Device Used to Improve Skin Hydration · NA · recruiting
- NCT06821867 — Efficacy and Safety of PN+HA (NEWEST) for the Improvement of Skin Hydration · NA · completed
- NCT06809543 — Clinical Benefits and Safety of Tropho Tend in the Management of Painful Rotator Cuff Tendinopathy · NA · recruiting
- NCT06821854 — Efficacy and Safety of PN20 (Plinest) for the Improvement of Skin Hydration · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05936437 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mastelli S.r.l
- Last refreshed: 12 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05936437.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing