Comparison of Noninvasively-Obtained Echocardiographic Doppler Parameters With Simultaneously-Measured Invasive Hemodynamics in Patients Referred for Right Heart Catheterization

NCT05935605 RECRUITING

The goal is to compare patients with and without varying severity of pulmonary vascular disease based upon hemodynamic signatures, echocardiographic measures, and lung ultrasound, in tandem with expired gas metabolic testing and blood sampling.

Details

Lead sponsor	Mayo Clinic
Status	RECRUITING
Enrolment	3000
Start date	2023-07-20
Completion	2028-05

Conditions

• Pulmonary Hypertension
• Pulmonary Vascular Disease
• Left Heart Disease

Interventions

• Transthoracic Echocardiography (TTE)
• Lung ultrasound

Primary outcomes

• Peak Exercise Cardiac Output — Baseline
  Peak exercise cardiac output (L/min) will be measured using the direct Fick technique during the invasive hemodynamic assessment by right heart catheterization.
• Peak Exercise Oxygen Consumption (VO2) — Baseline
  Peak exercise VO2 (ml/kg/min) will be measured using expired gas analysis collected during the invasive hemodynamic assessment by right heart catheterization.

Countries

United States