NCT05934123 (EMNODN-NEC) is a clinical trial of EMNODN NEC Care Bundle in Necrotising Enterocolitis Neonatal, sponsored by University Hospitals of Derby and Burton NHS Foundation Trust.

Who is sponsoring NCT05934123?

NCT05934123 is sponsored by University Hospitals of Derby and Burton NHS Foundation Trust.

What drugs are being tested in NCT05934123?

Interventions in NCT05934123: EMNODN NEC Care Bundle.

What condition does NCT05934123 study?

NCT05934123 studies Necrotising Enterocolitis Neonatal.

Is NCT05934123 still recruiting?

NCT05934123 is currently completed. Last updated 8 September 2025.

Last reviewed 2025-09-08 · How we verify

NCT05934123: EMNODN-NEC

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effects of Implementation of a Care Bundle on Rates of NEC and Own Mother's Milk Feeding in the East Midlands

Completed Last updated 8 September 2025

What this trial tests

trial testing EMNODN NEC Care Bundle in Necrotising Enterocolitis Neonatal in 53,600 participants. Completed in 31 May 2025.

Timeline

1 December 2022

Primary endpoint
30 September 2024

31 May 2025

Quick facts

Lead sponsor	University Hospitals of Derby and Burton NHS Foundation Trust
Status	Completed
Study type	OBSERVATIONAL
Enrollment	53,600
Start date	1 December 2022
Primary completion	30 September 2024
Estimated completion	31 May 2025
Sites	1 location across United Kingdom

Drugs / interventions tested

EMNODN NEC Care Bundle

Conditions studied

Necrotising Enterocolitis Neonatal — all drugs for Necrotising Enterocolitis Neonatal →

Sponsor

University Hospitals of Derby and Burton NHS Foundation Trust

Who can join

Eligibility, any sex, with Necrotising Enterocolitis Neonatal. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Necrotising enterocolitis (NEC) is a life-threatening gut disease in babies born early. Feeding preterm babies their own mother's milk prevents NEC. Fewer babies in the East Midlands get their own mother's milk than the national average, and more babies get NEC. The East Midlands Neonatal Operational Delivery Network (EMNODN) has created a care bundle to increase own mothers' milk feeding and reduce rates of NEC among babies born more than 8 weeks early, who are at the greatest risk of NEC. The care bundle describes the support that parents can expect to receive to help mothers feed their breastmilk to their babies. It also provides guidelines to help neonatal units ensure babies receive optimum nutritional care. This study will find whether this bundle is effective in helping more babies receive their own mothers' milk and in reducing NEC. It will also identify how well the bundle was introduced and which parts of the bundle were most helpful. The study team will answer these questions by collecting and studying data from babies' medical records.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Effects of implementation of a care bundle on rates of necrotising enterocolitis and own mother's milk feeding in the East Midlands: protocol for a mixed methods impact and process evaluation study.
Abramson J, Szatkowski L, Bains M, Orton E, et al · · 2024 · cited 4× · PMID 38816042 · DOI 10.1136/bmjopen-2023-078633

Verify or expand the search:

Other University Hospitals of Derby and Burton NHS Foundation Trust trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05934123 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Hospitals of Derby and Burton NHS Foundation Trust
Last refreshed: 8 September 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05934123.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing