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NCT05932628: TOPS
Thumb Osteoarthritis Prognosis for Supported Self-managment
trial testing This study will observe participants who receive a supported self management approach for thumb base osteoarthritis but it is not an interventional study. in Osteoarthritis Thumb in 150 participants. Participants enrolled and being followed up; not accepting new ones.
1 March 2025
Quick facts
| Lead sponsor | University Hospitals of Derby and Burton NHS Foundation Trust |
|---|---|
| Status | Active, enrolled |
| Study type | OBSERVATIONAL |
| Enrollment | 150 |
| Start date | 8 August 2023 |
| Primary completion | 1 March 2025 |
| Estimated completion | 1 August 2025 |
| Sites | 4 locations across United Kingdom |
Drugs / interventions tested
- This study will observe participants who receive a supported self management approach for thumb base osteoarthritis but it is not an interventional study.
Conditions studied
- Osteoarthritis Thumb — all drugs for Osteoarthritis Thumb →
Sponsor
University Hospitals of Derby and Burton NHS Foundation Trust
Who can join
30 and older, any sex, with Osteoarthritis Thumb. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Background Thumb base osteoarthritis (OA) is common in adults 40 years and over. It affects a person's ability to work, be independent and care for others. Sufferers complain of severe pain and difficulty in completing everyday tasks. The main treatment for the condition is advice on how a person can manage their condition (self-management), reduce their pain, strengthen their hands with exercises and practical tips on tackling painful tasks, sometimes providing a hand splint for support. The treatment is provided by occupational and physiotherapists. We know that this treatment helps suffers in the short term (up to three months). But the research was done in people with few other health problems and while self-management support helps provide pain relief for most people, there are some people who don't benefit. The aim of this research is to see how pain and other hand problems change over a period of six months after the start of treatment, to understand people's experience of care, and examine why some people improve, and some do not. Research Plan In patients receiving treatment for thumb base OA at four NHS sites, who are willing to take part, this research will: - 1. Record changes in symptoms and quality of life at three and six months from when treatment began in a postal questionnaire/survey. 2. Discuss the experience of care and people's beliefs about what makes treatment a success by interviewing a small group of patients. 3. Analyse patient characteristics, to see if it is possible to determine how they will respond to treatment. 4. Develop recommendations for improving care.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05932628
- Europe PMC full search
- ASCO Meeting Library
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Related trials
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Other University Hospitals of Derby and Burton NHS Foundation Trust trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05932628 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospitals of Derby and Burton NHS Foundation Trust
- Last refreshed: 27 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05932628.
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