NCT05930678 (VENT OR NOT) is a NA clinical trial of No ventilation with face mask in Morbid Obesity, sponsored by Nantes University Hospital.

Who is sponsoring NCT05930678?

NCT05930678 is sponsored by Nantes University Hospital.

What drugs are being tested in NCT05930678?

Interventions in NCT05930678: No ventilation with face mask, Ventilation with face mask.

What condition does NCT05930678 study?

NCT05930678 studies Morbid Obesity, Ventilation Therapy; Complications.

Is NCT05930678 still recruiting?

NCT05930678 is currently completed. Last updated 12 March 2026.

Last reviewed 2026-03-12 · How we verify

NCT05930678: VENT OR NOT

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Intubation of Obese Patients in the Operating Room With or Without Face Mask Ventilation

Completed NA Last updated 12 March 2026

What this trial tests

NA trial testing No ventilation with face mask in Morbid Obesity in 725 participants. Completed in 3 July 2025.

Timeline

12 September 2023

Primary endpoint
24 June 2025

3 July 2025

Quick facts

Lead sponsor	Nantes University Hospital
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	supportive care
Enrollment	725
Start date	12 September 2023
Primary completion	24 June 2025
Estimated completion	3 July 2025
Sites	13 locations across France

Drugs / interventions tested

No ventilation with face mask
Ventilation with face mask

Conditions studied

Morbid Obesity — all drugs for Morbid Obesity →
Ventilation Therapy; Complications — all drugs for Ventilation Therapy; Complications →

Sponsor

Nantes University Hospital

Who can join

18 and older, any sex, with Morbid Obesity or Ventilation Therapy; Complications. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the study is to answer a daily question in the operating room: what is the safest technique for intubation of severe/morbid obese patients (BMI 35 or more). There is a great heterogeneity of practices on the subject, so the principle is to determine a common practice to facilitate the management of these patients.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Intubation of obese patients in the operating room with or without bag-mask ventilation: study protocol for a randomized multicenter trial (VENT OR NOT).
Znaïdi S, Deransy R, Asehnoune K, Le Penndu M, et al · · 2025 · cited 2× · PMID 41219812 · DOI 10.1186/s13063-025-09114-z
Intubation of obese patients in the operating room with or without bag-mask ventilation: study protocol for a randomized multicenter trial (VENT OR NOT)
Znaïdi S, Deransy R, Asehnoune K, Penndu ML, et al · · 2025 · DOI 10.21203/rs.3.rs-4693821/v1

Verify or expand the search:

Other recruiting trials for Morbid Obesity

Currently open trials in the same condition.

NCT06689241 — Rivaroxaban Versus Enoxaparin for Prophylaxis of Venous Thromboembolism in Bariatric Surgery · NA · recruiting
NCT06413264 — Ultrasonography Guided Pneumoperitoneum for Laparoscopic Surgery in Morbidly Obese Patients · NA · recruiting
NCT07289555 — Tailored Stapled SADI-S: Initial Report and Preliminary Results · NA · recruiting
NCT07263269 — Comparing Dumping Symptoms and Quality of Life 6 Months After Sleeve Gastrectomy With or Without Transit Bipartition in · NA · active not recruiting
NCT06293703 — Effect of Limb Length Ratio on Roux-en-Y Gastric Bypass Outcomes (CLIMB II Study) · NA · recruiting

Other Nantes University Hospital trials

Trials by the same sponsor.

NCT07278661 — Preoperative Use of Romiplostim in Thrombocytopenic Patients Undergoing Cardiac Surgery. · Phase 2 · recruiting
NCT06681363 — Creation of a Biocollection of Patients With Acute Myeloid Leukemia (AML) or Lymphoid Leukemia (ALL) or High-risk Myelod · not yet recruiting
NCT07467382 — GOAT (Gait Observation of Achilles Tendon) · not yet recruiting
NCT07490379 — Comparison of the Efficacy of Transcranial Direct Current Stimulation at Home Versus in Hospital Settings in Patients Wi · NA · not yet recruiting
NCT07423481 — Weight Trajectories and Predictive Factors After Semaglutide in Patients With Grade 3 and Complicated Obesity · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05930678 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Nantes University Hospital
Last refreshed: 12 March 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05930678.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing