Who is sponsoring NCT05929573?

NCT05929573 is sponsored by Antalya Training and Research Hospital.

What drugs are being tested in NCT05929573?

Interventions in NCT05929573: Neutrophil Gelatinase-Associated Lipocalin, Renal Doppler Resistive Index.

What condition does NCT05929573 study?

NCT05929573 studies Acute Kidney Injury.

Is NCT05929573 still recruiting?

NCT05929573 is currently completed. Last updated 30 July 2024.

Last reviewed 2024-07-30 · How we verify

NCT05929573

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

RDRI and NGAL in Acute Kidney Injury in Abdominal Surgery

Completed Last updated 30 July 2024

What this trial tests

trial testing Neutrophil Gelatinase-Associated Lipocalin in Acute Kidney Injury in 43 participants. Completed in 20 July 2024.

Timeline

1 July 2023

Primary endpoint
31 December 2023

20 July 2024

Quick facts

Lead sponsor	Antalya Training and Research Hospital
Status	Completed
Study type	OBSERVATIONAL
Enrollment	43
Start date	1 July 2023
Primary completion	31 December 2023
Estimated completion	20 July 2024
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

Neutrophil Gelatinase-Associated Lipocalin
Renal Doppler Resistive Index

Conditions studied

Acute Kidney Injury — all drugs for Acute Kidney Injury →

Sponsor

Antalya Training and Research Hospital

Who can join

18 and older, any sex, with Acute Kidney Injury. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Acute kidney injury (AKI), which can occur after major surgeries, leads to increased morbidity and mortality if not detected and managed promptly. In clinical practice, serum creatinine and urine output values of patients are monitored to detect AKI, but these parameters can cause delays in diagnosis. Additionally, studies have been conducted on biomarkers such as Neutrophil Gelatinase-Associated Lipocalin (NGAL) and cystatin C in recent years, but definitive results have not been achieved. Renal Doppler Resistive Index (RDRI) is a non-invasive index believed to reflect renal vascular perfusion. RDRI measurement is a repeatable, inexpensive, and easy-to-apply technique. RDRI has been found to be associated with AKI in conditions such as renal dysfunction, hypertension, and post-traumatic hemorrhagic shock. Furthermore, due to the impact on renal perfusion in patients undergoing major surgery, RDRI, which reflects renal vascular resistance, can serve as an indicator of kidney perfusion. The aim of this study is to test the hypothesis, 'Does measuring postoperative RDRI in major abdominal surgery cases yield higher sensitivity and specificity values in detecting acute kidney injury compared to NGAL?'

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

Other recruiting trials for Acute Kidney Injury

Currently open trials in the same condition.

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NCT07262320 — Epidemiology and Processes of Care for Renal Replacement Therapy in Acute Kidney Injury in Latin America · recruiting
NCT07351149 — Postoperative Acute Kidney Injury in Children Undergoing Major Non-cardiac Surgery · recruiting
NCT07215702 — A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kid · Phase 2 · recruiting
NCT06654193 — Allogeneic HB-adMSCs vs Placebo for the Treatment of Acute Kidney Injury · Phase 1, PHASE2 · recruiting

Other Antalya Training and Research Hospital trials

Trials by the same sponsor.

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05929573 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Antalya Training and Research Hospital
Last refreshed: 30 July 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05929573.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing