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NCT05929508
Improving Mobility and Function Following Transfemoral Amputation: A Novel Approach to Reverse Volumetric Muscle Loss
NA trial testing Ischemic Preconditioning in Traumatic Amputation of Lower Extremity in 30 participants. Currently enrolling.
1 June 2027
Quick facts
| Lead sponsor | University of Illinois at Chicago |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | basic science |
| Enrollment | 30 |
| Start date | 1 April 2024 |
| Primary completion | 1 June 2027 |
| Estimated completion | 31 December 2027 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Ischemic Preconditioning — full drug profile →
Conditions studied
- Traumatic Amputation of Lower Extremity — all drugs for Traumatic Amputation of Lower Extremity →
Sponsor
University of Illinois at Chicago
Who can join
18 and older, any sex, with Traumatic Amputation of Lower Extremity. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to investigate the relationship between thigh strength and walking ability and assess if using a blood pressure cuff on the leg improves strength and walking performance.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05929508
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Ischemic Preconditioning
Trials testing the same drug.
- NCT07003113 — Ischemic Preconditioning in Osteoarthritis and Back Pain · NA · recruiting
- NCT07497659 — Ischemic Preconditioning in Resistance Exercise in Older Women · NA · completed
- NCT07117643 — Ischemic Preconditioning - Perspectives of Use Vivio/in Vitro Studies · NA · enrolling by invitation
- NCT07170774 — Research on the Enhancement of Aerobic Metabolic Energy Supply Capacity by Ischemic Preconditioning. · NA · completed
- NCT07146399 — The Impact of Ischemic Preconditioning on Exercise Performance and Physiological Function · NA · completed
Other University of Illinois at Chicago trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05929508 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Illinois at Chicago
- Last refreshed: 17 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05929508.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing