Last reviewed · How we verify
NCT05927103
Differences Between Coffee and Non-coffee Drinkers in the Gut Microbiome and Microbiota-Gut-Brain Axis
trial in Healthy in 62 participants. Completed in 18 January 2023.
18 January 2023
Quick facts
| Lead sponsor | University College Cork |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 62 |
| Start date | 21 September 2021 |
| Primary completion | 18 January 2023 |
| Estimated completion | 18 January 2023 |
| Sites | 1 location across Ireland |
Conditions studied
- Healthy — all drugs for Healthy →
Sponsor
University College Cork
Who can join
Adults 30 to 50, any sex, with Healthy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to investigate the potential of coffee to act as a prebiotic to alter gut microbiota and improve mood, memory and cognitive performance.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Habitual coffee intake shapes the gut microbiome and modifies host physiology and cognition.
Boscaini S, Bastiaanssen TFS, Moloney GM, Bergamo F, et al · · 2026 · PMID 42014402 · DOI 10.1038/s41467-026-71264-8
Verify or expand the search:
- PubMed search for NCT05927103
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Healthy
Currently open trials in the same condition.
- NCT06707207 — Predicting Future Errors During Skill Performance · recruiting
- NCT07169630 — PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI) · Phase 1 · recruiting
- NCT07499414 — The Effects of the Bile Acid Supplement, 7-keto Lithocholic Acid, on Human Gut Microbiota and Risk Factors for Disease. · NA · recruiting
- NCT07496697 — Effects of Electroacupuncture at NP82 and SP15 on Bowel Motility in Healthy Subjects · NA · recruiting
- NCT06431932 — Pilot Trial of Fisetin in Healthy Volunteers and Older Patients With Multimorbidity · Phase 1, PHASE2 · recruiting
Other University College Cork trials
Trials by the same sponsor.
- NCT07481240 — A Household-Based Dietary Intervention Study of Vitamin D Fortified Bread in Irish Families · NA · recruiting
- NCT06857539 — Assessing Intellectual and Motor Outcomes in High-risk Infants · not yet recruiting
- NCT07363928 — A Digital Cognitive Behavioural Therapy for Insomnia Intervention in Mild Cognitive Impairment and Mild Dementia · NA · completed
- NCT06705582 — OASIS Study: Vitamin D Deficiency Prevention Among Older Adults in Ireland · NA · completed
- NCT06709209 — AI-driven Narrow-band Imaging Score for Disease Assessment and Outcome Prediction in Ulcerative Colitis · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05927103 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University College Cork
- Last refreshed: 3 July 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05927103.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing