NCT05925725 is a Phase 4 clinical trial of • harpagozid • boswellin = LOXACON in Osteo Arthritis Knee, sponsored by Polyclinic of the Hospitaller Brothers of St. John of God, Budapest.

Who is sponsoring NCT05925725?

NCT05925725 is sponsored by Polyclinic of the Hospitaller Brothers of St. John of God, Budapest.

What drugs are being tested in NCT05925725?

Interventions in NCT05925725: • harpagozid • boswellin = LOXACON.

What condition does NCT05925725 study?

NCT05925725 studies Osteo Arthritis Knee.

Is NCT05925725 still recruiting?

NCT05925725 is currently completed. Last updated 15 November 2023.

Last reviewed 2023-11-15 · How we verify

NCT05925725

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Clinical Efficacy and Safety of Loxacon Dietary Supplement Capsules at Patients With Knee Arthrosis

Completed Phase 4 Last updated 15 November 2023

What this trial tests

Phase 4 trial testing • harpagozid • boswellin = LOXACON in Osteo Arthritis Knee in 100 participants. Completed in 6 September 2023.

Timeline

25 January 2023

Primary endpoint
5 May 2023

6 September 2023

Quick facts

Lead sponsor	Polyclinic of the Hospitaller Brothers of St. John of God, Budapest
Phase	Phase 4
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	quadruple
Primary purpose	health services research
Enrollment	100
Start date	25 January 2023
Primary completion	5 May 2023
Estimated completion	6 September 2023
Sites	1 location across Hungary

Drugs / interventions tested

• harpagozid • boswellin = LOXACON — full drug profile →

Conditions studied

Osteo Arthritis Knee — all drugs for Osteo Arthritis Knee →

Sponsor

Polyclinic of the Hospitaller Brothers of St. John of God, Budapest

Who can join

Adults 40 to 80, any sex, with Osteo Arthritis Knee. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The study will be a multicenter, randomized, double-blind, follow-up clinical trial. Neither the examining doctor nor the patient knows which capsule they will receive. Just the test unlock the codes after completion. T

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Osteoarthritis: Insights into Diagnosis, Pathophysiology, Therapeutic Avenues, and the Potential of Natural Extracts.
Coppola C, Greco M, Munir A, Musarò D, et al · · 2024 · cited 19× · PMID 38785519 · DOI 10.3390/cimb46050251

Verify or expand the search:

Other recruiting trials for Osteo Arthritis Knee

Currently open trials in the same condition.

NCT07258693 — Multimodal Treatment of Knee Osteoarthritis: Therapeutic Exercise and Noninvasive Neuromodulation (NESA) Versus Therapeu · NA · active not recruiting
NCT07141316 — Effects of Blood Flow Restriction Combined With Electrostimulation After Knee Arthroplasty · NA · active not recruiting
NCT06485843 — An Study to Evaluate Safety and Tolerability of OA-SYS in Subjects With Moderate to Severe Osteoarthritis of the Knee Jo · Phase 2 · recruiting
NCT06965946 — Intermittent Hypoxia-Hyperoxia Combined With Physical Therapy for Knee Osteoarthritis · NA · recruiting
NCT06058169 — Effects of Home Base Whole-body Vibration in Osteoarthritis. (VIBE-Rx2) · NA · recruiting

Other Polyclinic of the Hospitaller Brothers of St. John of God, Budapest trials

Trials by the same sponsor.

NCT07005375 — The Effect of Bathing in the Thermal Mineral Water on the Pain and Performance of Athletes · NA · enrolling by invitation
NCT05342051 — The Effects of Immersion in 42℃ Thermal-mineral Water on Chronic Low-back Pain · NA · completed
NCT04485182 — Underwater Jet Massage Therapy for Chronic Low Back Pain · terminated
NCT04392791 — Does Balnotherapy Influence the Qualitiy of Life in SLE · NA · completed
NCT03488498 — Weight Bath Traction in Chronic Low Back Pain · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05925725 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Polyclinic of the Hospitaller Brothers of St. John of God, Budapest
Last refreshed: 15 November 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05925725.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing