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NCT05924737: RECOPS

Delta Waves and Cognitive Recovery

Completed NA Last updated 24 June 2024
What this trial tests

NA trial testing Sleep deprivatin in Sleep Deprivation in 45 participants. Completed in 30 April 2024.

Timeline
1 October 2023
Primary endpoint
30 March 2024
30 April 2024

Quick facts

Lead sponsorInstitut de Recherche Biomedicale des Armees
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposescreening
Enrollment45
Start date1 October 2023
Primary completion30 March 2024
Estimated completion30 April 2024
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

Institut de Recherche Biomedicale des Armees

Who can join

Adults 18 to 45, any sex, with Sleep Deprivation or Cognitive Impairment. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In a laboratory protocol in healthy adults, exposed to a prolonged period of wakefulness with a restricted opportunity for sleep (40h of wakefulness / 3h of sleep / 21h of wakefulness), we hypothesize that the relative increase in spectral power of Delta waves \[ 1 - 4 Hz\] in NREM in the frontal territory, identified as a potential marker of the restorative function of sleep, during a night of sleep with limited recovery (3 h of time in bed) after sleep deprivation (40 h of continuous wakefulness), will be less important in subjects with poor recovery in terms of cognitive performance than in those with good recovery.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. A Functional <i>HMOX2</i> Genetic Variant Is Associated with Resting Diastolic and Mean Arterial Pressure in Healthy Humans.
    Beauchamps V, Touron J, Gomez-Merino D, Lagraniere A, et al · · 2026 · PMID 42072159 · DOI 10.3390/antiox15040518
  2. Short sleep recovery partially restores decision-making alterations induced by total sleep deprivation.
    Schlitter Q, Beauchamps V, Quiquempoix M, Fabries P, et al · · 2026 · PMID 42040193 · DOI 10.1093/sleepadvances/zpag038

Verify or expand the search:

Other recruiting trials for Sleep Deprivation

Currently open trials in the same condition.

Other Institut de Recherche Biomedicale des Armees trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing