NCT05922956 (REF-BIP) is a NA clinical trial of Facial emotion recognition test in Social Cognition, sponsored by Centre Hospitalier Universitaire, Amiens.

Who is sponsoring NCT05922956?

NCT05922956 is sponsored by Centre Hospitalier Universitaire, Amiens.

What drugs are being tested in NCT05922956?

Interventions in NCT05922956: Facial emotion recognition test.

What condition does NCT05922956 study?

NCT05922956 studies Social Cognition, Facial Emotion Recognition, Facial Affect, Bipolar Disorder I and II.

Is NCT05922956 still recruiting?

NCT05922956 is currently completed. Last updated 19 November 2025.

Last reviewed 2025-11-19 · How we verify

NCT05922956: REF-BIP

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Facial Emotion Recognition in Patients With Euthymic Bipolar Disorder I and II

Completed NA Last updated 19 November 2025

What this trial tests

NA trial testing Facial emotion recognition test in Social Cognition in 10 participants. Completed in 1 July 2023.

Timeline

1 April 2020

Primary endpoint
1 May 2023

1 July 2023

Quick facts

Lead sponsor	Centre Hospitalier Universitaire, Amiens
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	other
Enrollment	10
Start date	1 April 2020
Primary completion	1 May 2023
Estimated completion	1 July 2023
Sites	1 location across France

Drugs / interventions tested

Facial emotion recognition test

Conditions studied

Social Cognition — all drugs for Social Cognition →
Facial Emotion Recognition — all drugs for Facial Emotion Recognition →
Facial Affect — all drugs for Facial Affect →
Bipolar Disorder I and II — all drugs for Bipolar Disorder I and II →

Sponsor

Centre Hospitalier Universitaire, Amiens

Who can join

18 and older, any sex, with Social Cognition or Facial Emotion Recognition. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The facial emotion recognition is a basic social skill for successful social interactions. Several meta-analyses and recent studies found impairments of the perception of facial emotions in patients with euthymic bipolar disorder. Few studies compared recognition of facial emotions impairments during euthymia in patients with bipolar disorder type 1 and 2. These studies included low population samples (N\<60). There were discrepancies in results of these studies. Szanto suggested that facial emotion recognition impairments were correlated with suicidal risk and social isolation. These impairments should be taking into account regarding psycho-social treatments in patients with bipolar disorder. This study aims to evaluate facial emotion recognition in patients with bipolar I and II disorders compared to healthy controls, using the facial emotion recognition test (TREF). The objective of the present study is to compare TREF scores in a group of patients with bipolar 1, a group of patients with bipolar 2 disorder and a group with healthy controls. In addition, the investigators will investigate the relationships between TREF scores and levels of self-esteem and mental well-being.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

Verify or expand the search:

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Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05922956 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Centre Hospitalier Universitaire, Amiens
Last refreshed: 19 November 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05922956.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing