NCT05919810 is a NA clinical trial of Probiotic in Acne Vulgaris, sponsored by Integrative Skin Science and Research.

Who is sponsoring NCT05919810?

NCT05919810 is sponsored by Integrative Skin Science and Research.

What drugs are being tested in NCT05919810?

Interventions in NCT05919810: Probiotic, Oral herbal powder supplement.

What condition does NCT05919810 study?

NCT05919810 studies Acne Vulgaris, Acneiform Eruptions, Skin Diseases, Sebaceous Gland Diseases.

Is NCT05919810 still recruiting?

NCT05919810 is currently completed. Last updated 18 December 2024.

Last reviewed 2024-12-18 · How we verify

NCT05919810

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effects of Oral Probiotics and Herbal Supplementation on the Gut Microbiome and Sebum Excretion Rate in Non-Cystic Acne

Completed NA Last updated 18 December 2024

What this trial tests

NA trial testing Probiotic in Acne Vulgaris in 36 participants. Completed in 31 July 2024.

Timeline

3 July 2023

Primary endpoint
12 February 2024

31 July 2024

Quick facts

Lead sponsor	Integrative Skin Science and Research
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	36
Start date	3 July 2023
Primary completion	12 February 2024
Estimated completion	31 July 2024
Sites	1 location across United States

Drugs / interventions tested

Probiotic
Oral herbal powder supplement

Conditions studied

Acne Vulgaris — all drugs for Acne Vulgaris →
Acneiform Eruptions — all drugs for Acneiform Eruptions →
Skin Diseases — all drugs for Skin Diseases →
Sebaceous Gland Diseases — all drugs for Sebaceous Gland Diseases →

Sponsor

Integrative Skin Science and Research

Who can join

Adults 12 to 45, any sex, with Acne Vulgaris or Acneiform Eruptions. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to evaluates how probiotics and dietary supplementation with an herbal powder can shift the gut microbiome in those with non-cystic acne vulgaris.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Prospective Comparative Study of an Oral Synbiotic and a Myoinositol-Based Herbal Supplement in Modifying Hormone Levels and the Gut Microbiome in Non-cystic Acne.
Min M, Afzal N, Maloh J, Dulai AS, et al · · 2025 · cited 3× · PMID 40246799 · DOI 10.1007/s13555-025-01411-4

Verify or expand the search:

Other trials of Probiotic

Trials testing the same drug.

NCT07529457 — Akk09 in Adults With Constipation · NA · not yet recruiting
NCT07507955 — Probiotics for Constipation Relief in Adults · NA · not yet recruiting
NCT07462481 — Probiotic Improve Constipation · NA · recruiting
NCT07511855 — Stress-buffering and Sleep Disturbance-resilient Effects of a Dual Bifidobacterium Longum Combination Under Short-term T · Phase 2 · not yet recruiting
NCT07474064 — Probiotics Combined With Targeted Therapy Plus Immunotherapy in Bladder-Preserving Setting for Patients With MIBC · Phase 2 · not yet recruiting

Other recruiting trials for Acne Vulgaris

Currently open trials in the same condition.

NCT07341087 — Skin Inflammation in Perimenopause: A Probiotic Intervention Proof of Concept Trial · NA · recruiting
NCT07474883 — Efficacy of 0.5% Topical Timolol Eye Drops in the Treatment of Post-Inflammatory Erythema Following Acne Vulgaris · EARLY_PHASE1 · recruiting
NCT07186413 — A Study to Compare the Efficacy, Safety and Pharmacokinetics of Trifarotene 50 mcg/g Cream in Chinese Subjects With Acne · Phase 3 · recruiting
NCT07056673 — Cold Atmospheric Plasma for Moderate-to-severe Acne Vulgaris Study · NA · recruiting
NCT07102186 — Efficacy and Safety of Adapalene Gel and Hyaluronic Acid Versus Adapalene Gel Alone in Mild to Moderate Acne Vulgaris · Phase 4 · recruiting

Other Integrative Skin Science and Research trials

Trials by the same sponsor.

NCT06571721 — The Effects of Topical Almond Oil and Tretinoin on Facial Wrinkles · NA · recruiting
NCT06146166 — The Effects of an Oral Hair Supplement on Hair Density, Growth, and Microbiome · NA · active not recruiting
NCT06146140 — Effects of an Oral Herbal Supplement on Skin Aging, Hydration, and Elasticity · NA · unknown
NCT06072066 — Effects of Oral Supplement Containing L-Histidine and Antioxidants on the Skin Barrier Function and Systemic Inflammatio · NA · recruiting
NCT06142487 — Assessment of the Effects of Silk Pillowcases on Acne Prone Skin · NA · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05919810 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Integrative Skin Science and Research
Last refreshed: 18 December 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05919810.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing