NCT05915299 is a clinical trial of OCS Heart in Heart Transplant, sponsored by TransMedics.

Who is sponsoring NCT05915299?

NCT05915299 is sponsored by TransMedics.

What drugs are being tested in NCT05915299?

Interventions in NCT05915299: OCS Heart.

What condition does NCT05915299 study?

NCT05915299 studies Heart Transplant.

Is NCT05915299 still recruiting?

NCT05915299 is currently recruiting now. Last updated 30 October 2025.

Last reviewed 2025-10-30 · How we verify

NCT05915299

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

US National OCS Heart Perfusion (OHP) Registry

Recruiting now Last updated 30 October 2025

What this trial tests

trial testing OCS Heart in Heart Transplant in 100,000 participants. Currently enrolling.

Timeline

25 August 2023

Primary endpoint
31 August 2029

31 August 2033

Quick facts

Lead sponsor	TransMedics
Status	Recruiting now
Study type	OBSERVATIONAL
Enrollment	100,000
Start date	25 August 2023
Primary completion	31 August 2029
Estimated completion	31 August 2033
Sites	37 locations across United States

Drugs / interventions tested

OCS Heart

Conditions studied

Heart Transplant — all drugs for Heart Transplant →

Sponsor

TransMedics — full company profile →

Who can join

Eligibility, any sex, with Heart Transplant. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This Registry is a sponsor initiated, multi-center, observational post-approval registry with independent academic oversight.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other recruiting trials for Heart Transplant

Currently open trials in the same condition.

NCT06625073 — Randomized Trial of SGLT2i in Heart Transplant Recipients · Phase 4 · recruiting
NCT05025774 — Fitness and Lung Function Among Survivors of Heart Transplant, Leukemia and Infant BPD Through Exercise · recruiting
NCT06478017 — Belatacept in Heart Transplantation · Phase 2 · recruiting
NCT07125703 — Observational Study With Additional Procedures: Metabolomic and Ultrastructural Findings of Allograft in Heart Transplan · active not recruiting
NCT06426173 — Effect of Resistance Training in Patients on the Waiting List for Heart Transplant · NA · recruiting

Other TransMedics trials

Trials by the same sponsor.

NCT04615182 — Donor After Circulatory Death Heart CAP Trial · NA · completed
NCT04194437 — OCS Liver DCD Trial · NA · terminated
NCT05096754 — OCS Liver PROTECT Continued Access Protocol (CAP) Continuation Post-Approval Study · completed
NCT04186221 — OCS Liver PROTECT Continued Access Protocol · NA · completed
NCT03831048 — Donors After Circulatory Death Heart Trial · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05915299 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by TransMedics
Last refreshed: 30 October 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05915299.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing