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NCT05912465: LUCAPET

Predicting Lung Cancer-Associated Cachexia With PET Imaging

Status unknown NA Last updated 27 June 2023
What this trial tests

NA trial testing Stress Reduction Training in Cachexia in 150 participants. Status unknown.

Timeline
1 July 2023
Primary endpoint
1 July 2024
1 March 2025

Quick facts

Lead sponsorMedical University of Vienna
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationna
Designsingle group
Maskingnone
Primary purposediagnostic
Enrollment150
Start date1 July 2023
Primary completion1 July 2024
Estimated completion1 March 2025
Sites3 locations across Austria, Germany, Italy

Drugs / interventions tested

Conditions studied

Sponsor

Medical University of Vienna

Who can join

18 and older, any sex, with Cachexia or Lung Neoplasm. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This prospective observational study aims to investigate the relationship between cancer cachexia, stress levels, and metabolic changes in 150 lung cancer patients. Cancer cachexia, characterized by weight loss and muscle wasting, significantly impacts patient outcomes. Psychological stress is thought to contribute to cachexia development. Assessments will include medical history, physical examinations, laboratory tests, and imaging. Cancer cachexia will be diagnosed based on weight loss, reduced food intake, and inflammation markers. Psychological stress will be evaluated using questionnaires and biomarkers. Metabolic changes will be assessed using positron emission tomography-computed tomography (PET-CT) scans. The primary objective is to determine differences in metabolic activity between cachectic and non-cachectic patients. Secondary objectives include evaluating changes in brain activity and exploring the relationship between stress, inflammation, and metabolism.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Systemic Metabolic and Volumetric Assessment via Whole-Body [<sup>18</sup>F]FDG-PET/CT: Pancreas Size Predicts Cachexia in Head and Neck Squamous Cell Carcinoma.
    Yu J, Spielvogel C, Haberl D, Jiang Z, et al · · 2024 · cited 6× · PMID 39409971 · DOI 10.3390/cancers16193352

Verify or expand the search:

Other recruiting trials for Cachexia

Currently open trials in the same condition.

Other Medical University of Vienna trials

Trials by the same sponsor.

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