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NCT05909215
Attenuation Of Hemodynamic Response To Laryngoscopy. Role Of Dexmedetomidine. A Dose Finding Study
Phase 4 trial testing Normal saline in Hemodynamic Instability in 105 participants. Completed in 13 December 2021.
13 December 2021
Quick facts
| Lead sponsor | Sindh Institute of Urology and Transplantation |
|---|---|
| Phase | Phase 4 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 105 |
| Start date | 23 August 2021 |
| Primary completion | 13 December 2021 |
| Estimated completion | 13 December 2021 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- Normal saline
- Dexmedetomidine 0.5 microgram/kg — full drug profile →
- Dexmedetomidine 0.75 microgram/kg — full drug profile →
Conditions studied
- Hemodynamic Instability — all drugs for Hemodynamic Instability →
- Tracheal Intubation — all drugs for Tracheal Intubation →
- Dexmedetomidine — all drugs for Dexmedetomidine →
Sponsor
Sindh Institute of Urology and Transplantation
Who can join
Adults 18 to 55, any sex, with Hemodynamic Instability or Tracheal Intubation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Two doses of Dexmedetomidine (0.5 µ/kg and 0.75 µ/kg) will be used to attenuate the stress response to laryngoscopy in American Society of Anesthesiology, physical class I patients which will be compared with the placebo-controlled group.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05909215
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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Other Sindh Institute of Urology and Transplantation trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05909215 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Sindh Institute of Urology and Transplantation
- Last refreshed: 18 June 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05909215.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing