Who is sponsoring NCT05908851?

NCT05908851 is sponsored by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's.

What condition does NCT05908851 study?

NCT05908851 studies Shoulder Arthritis, Anesthesia, Local, Local Infiltration.

What drugs are being tested in NCT05908851?

Interventions: 100 mL of 0.9% normal saline (57ml), 0.5% ropivacaine (40 ml), 10 mg morphine (10 mg/ml), 0.1 mg of epinephrine (0.1 mg/ml), and 30 mg of ketorolac (30 mg/ml).

What is the status of NCT05908851?

NCT05908851 is currently UNKNOWN.

Last reviewed 2023-10-05 · How we verify

Perioperative Pain Management for Total Shoulder Arthroplasty: A Pilot Non-Inferiority Trial

NCT05908851 NA UNKNOWN

Total shoulder arthroplasty (TSA) is a common and effective treatment for end-stage shoulder pathologies. Over the past 25 years, implant designs have evolved and the indications for joint replacement have expanded significantly to include arthritis, rotator cuff arthropathy, complex shoulder trauma and trauma sequelae. This has resulted in a worldwide increase in rates of shoulder replacement surgery. The concomitant increased treatment burden for health care systems has prompted interest in strategies to improve the effectiveness and efficiency of patient care such as streamlining intraoperative procedures, mitigating complications, and reducing length of stay by providing outpatient surgical care. Outpatient lower extremity arthroplasty is commonplace and provides helpful information that can guide the development of outpatient TSA such as careful patient selection and the use of standardized perioperative pain management protocols. In lower extremity arthroplasty, several authors have described challenges associated with nerve blockade and the advantages of high-volume local infiltration analgesia (LIA) for outpatient arthroplasty. Proponents of outpatient TSA also describe the importance of patient selection, standardized perioperative protocols and implementation of comprehensive perioperative pain management strategies that can include the use of perioperative ultrasound guided interscalene brachial plexus blockade with a "single shot" injection, ultrasound guided interscalene brachial plexus blockade with a temporary indwelling catheter (ISB), LIA near the surgical site, and multimodal postoperative analgesics.

Details

Lead sponsor	London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Phase	NA
Status	UNKNOWN
Enrolment	80
Start date	Wed Nov 01 2023 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Sat Nov 01 2025 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Shoulder Arthritis
Anesthesia, Local
Local Infiltration

Interventions

100 mL of 0.9% normal saline (57ml), 0.5% ropivacaine (40 ml), 10 mg morphine (10 mg/ml), 0.1 mg of epinephrine (0.1 mg/ml), and 30 mg of ketorolac (30 mg/ml)

Countries

Canada