Evaluation of the Effect of Acetylcysteine and Vitamin E on Psoriasis Vulgaris Patients During The Active Phase

NCT05906498 Phase 3 UNKNOWN

This study aims to assess the effect of adding N-acetyl cysteine (NAC) alone or in combination with Vitamin E to conventional therapy in improving the clinical outcome, oxidative stress, and inflammation in patients with mild psoriasis vulgaris

Details

Lead sponsor	Badr University
Phase	Phase 3
Status	UNKNOWN
Enrolment	60
Start date	2022-12-01
Completion	2023-12

Conditions

• Psoriasis Vulgaris

Interventions

• Acetyl cysteine
• Vitamin E

Primary outcomes

• level of interleukin-36(IL-36 gamma) (Pg/ml) — 4 months
  measuring level of interleukin-36(IL-36 gamma) at baseline before the intervention and during taking the intervention and 1 month after stopping taking the intervention
• level of Malondialdehyde (MDA) (µmol/L) — 4 months
  measuring level of malondialdehyde (MDA) at baseline before the intervention and during taking the intervention and 1 month after stopping taking the intervention

Countries

Egypt