NCT05901337

Cupping Therapy on Immune System in Post Covid -19

Completed NA Last updated 13 June 2023

What this trial tests

NA trial testing Cupping therapy with convential medical treatment in Covid-19 Patients in 76 participants. Completed in 1 June 2023.

Timeline

7 March 2022

Primary endpoint
21 June 2022

1 June 2023

Quick facts

Lead sponsor	Cairo University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	76
Start date	7 March 2022
Primary completion	21 June 2022
Estimated completion	1 June 2023
Sites	1 location across Egypt

Drugs / interventions tested

• Cupping therapy with convential medical treatment
• Convential medical treatment — full drug profile →

Conditions studied

• Covid-19 Patients — all drugs for Covid-19 Patients →

Sponsor

Cairo University

Who can join

Adults 21 to 66, any sex, with Covid-19 Patients. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Purpose of this study is to investigate

1. The effect of Dry cupping therapy on T-Lymphocyte in post covid-19 patients.
2. The effect of Dry cupping therapy on serum Cytokine in post covid-19 patients.
3. The effect of Dry cupping therapy on Immunoglobulin IgA.
4. The effect of Dry cupping therapy on Immunoglobulin IgM.
5. The effect of Dry cupping therapy on Immunoglobulin IgG. seventy six patients of both genders with deficiency in T-Lymphocyte number,,higher level of serum cytokine and lower immunoglobulin IgA,IgM,IgG after two weeks of recovery from covid-19 . Age range from Twenty one to Sixty six years old .They participated in the study and recruited from surveillance unit of Shobra general hospital .These patients recruited by phone and have been offered to participate in the programme.The patients were divided equally into two groups (A and B). Assessment was done before and after treatment. T-Lymphocyte, serum cytokine and immunoglobulin IgA, IgM and IgG were analyzed by kenza 240 TX from fluorescence-labeled flow cytometry. Disposable cupping therapy instrument was used in treatment of group (A) in addition to traditional medical treatment in the form of vitamin C, D and anticoagulant drugs. Traditional medical treatment only was used in treatment of group (B).The obtained results of this study will determine the significant improvement of participated two groups.

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Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Personalized immunization to optimize vaccine immunogenicity: exploring the multidimensional effects of host intrinsic factors, external intervention strategies, and the external environment.
   Chen K, Gu S, Li J, Xu Y, et al · · 2025 · PMID 40936925 · DOI 10.3389/fimmu.2025.1655819