NCT05898204 (KEMESO) is a NA clinical trial of Ketogenic diet in Obesity, sponsored by University of Roma La Sapienza.

Who is sponsoring NCT05898204?

NCT05898204 is sponsored by University of Roma La Sapienza.

What drugs are being tested in NCT05898204?

Interventions in NCT05898204: Ketogenic diet, Balanced diet.

Is NCT05898204 still recruiting?

NCT05898204 is currently completed. Last updated 14 August 2025.

Last reviewed 2025-08-14 · How we verify

NCT05898204: KEMESO

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

KEtogenic Diet and Its Multiple EffectS on Obesity

Completed NA Last updated 14 August 2025

What this trial tests

NA trial testing Ketogenic diet in Obesity in 24 participants. Completed in 23 June 2022.

Timeline

3 February 2022

Primary endpoint
6 May 2022

23 June 2022

Quick facts

Lead sponsor	University of Roma La Sapienza
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	24
Start date	3 February 2022
Primary completion	6 May 2022
Estimated completion	23 June 2022
Sites	1 location across Italy

Drugs / interventions tested

Ketogenic diet — full drug profile →
Balanced diet

Conditions studied

Obesity — all drugs for Obesity →

Sponsor

University of Roma La Sapienza

Who can join

Adults 18 to 65, any sex, with Obesity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The prevalence of obesity and metabolic disturbances is worryingly increasing worldwide, therefore the study of their pathophysiology is extremely important to find new strategies for their treatment. Obesity has a strong impact not only on the metabolism of the patients, but also may impact hormonal, inflammatory and immune profile, and profoundly influence the daily life of the patients. Weight loss may determine an amelioration of these parameters, but the impact of the diet composition aimed to weight loss on them has not been profoundly studied yet. The aim of our research project is to study the effects of a ketogenic diet in comparison with an isocaloric balanced diet on weight loss and anthropometric parameters, quality of life, hormone profile, sleep, sexual function, circadian rhythm, inflammatory and immunological parameters in obese patients.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Ketone body metabolism and cardiometabolic implications for cognitive health.
Fulghum K, Salathe SF, Davis X, Thyfault JP, et al · · 2024 · cited 11× · PMID 40093558 · DOI 10.1038/s44324-024-00029-y

Verify or expand the search:

Other trials of Ketogenic diet

Trials testing the same drug.

NCT07495267 — Nutritional Ketosis Marfan · NA · not yet recruiting
NCT07415590 — Ketogenic Diet for Post-Traumatic Stress Disorder (PTSD) · NA · not yet recruiting
NCT03991897 — Nutritional Ketosis: a Novel Metabolic Strategy to Treat Lymphedema Patients? · NA · recruiting
NCT07479095 — Low-glucose/High-fat Intake Dietary Regimen as a Tool for Empowering Diagnostic Accuracy of 2-[18F]FDG PET/CT in Lepidic · NA · recruiting
NCT06963437 — Interventions for Weight Regain After Bariatric Surgery · NA · completed

Other recruiting trials for Obesity

Currently open trials in the same condition.

NCT07403604 — Effect of Insulin Lowering on Lipogenesis · Phase 1 · recruiting
NCT07509307 — AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee · Phase 3 · recruiting
NCT07272837 — Impact of Semaglutide (Ozempic/Wegovy®) on Heart and Muscle Mass · recruiting
NCT07481630 — A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoart · Phase 3 · recruiting
NCT07527195 — Understanding the Effect of CagriSema, Cagrilintide, and Semaglutide on Muscle Health (Role of Amylin Signature in Muscl · Phase 1 · recruiting

Other University of Roma La Sapienza trials

Trials by the same sponsor.

NCT07485023 — Oral Versus Intravenous Iron for Anemia Diagnosed After 34 Weeks of Gestation · NA · not yet recruiting
NCT07305519 — The Combined Effect of Magnesium, Palmitoylethanolamide, High-Molecular-weight Hyaluronic Acid, Vitamin B6, and Vitamin · NA · not yet recruiting
NCT07520968 — ABX Versus CHX in NSPT: a RCT · NA · active not recruiting
NCT07109596 — Integration of Clinical, Biological and Psycho-social Variables for a Gender-sensitive Frailty Prediction · recruiting
NCT07490574 — Trial of Underwater Versus Gas-Insufflation Colorectal Endoscopic Submucosal DisseEtion · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05898204 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Roma La Sapienza
Last refreshed: 14 August 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05898204.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing