NCT05897125: TELE-TOC

Telehealth Education Leveraging Electronic Transitions Of Care for COPD Patients

ENROLLING BY INVITATION NA Last updated 14 January 2026

What this trial tests

NA trial testing Virtual at Home Medication Reconciliation Visit(s) in COPD Exacerbation in 218 participants. Enrolling by invitation.

Timeline

19 February 2025

Primary endpoint
31 August 2026

31 December 2026

Quick facts

Lead sponsor	University of Chicago
Phase	NA
Status	ENROLLING BY INVITATION
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	prevention
Enrollment	218
Start date	19 February 2025
Primary completion	31 August 2026
Estimated completion	31 December 2026
Sites	1 location across United States

Drugs / interventions tested

• Virtual at Home Medication Reconciliation Visit(s)
• Virtual At Home Medication Education Visit(s)
• COPD advanced practice nurse Inpatient Consult
• Inpatient Medication Reconciliation
• Post-discharge nurse 48 hour phone follow-up call
• Post-discharge follow-up advanced practice nurse outpatient visit

Conditions studied

• COPD Exacerbation — all drugs for COPD Exacerbation →
• Care Transitions — all drugs for Care Transitions →

Sponsor

University of Chicago

Who can join

18 and older, any sex, with COPD Exacerbation or Care Transitions. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Transitions of Care (TOC) between hospital, ambulatory, and home settings for high-risk, frequently hospitalized adults with chronic diseases, such as chronic obstructive pulmonary disease (COPD) are complex, costly, and vulnerable to safety threats and poor health outcomes. One potential solution to address this gap in care is the Transitional Care Model (TCM), which utilizes a patient-centered approach with in-home interventions; since in-person in-home visits are costly, using innovative telehealth, such as virtual visits via teleconferencing may be just as effective with greater feasibility, scalability, and sustainability, particularly in the post-COVID-19 era as has been seen the rapid expansion of these technologies. With a transdisciplinary team of experts from cognitive science, care transitions/handoffs, human factors engineering, design, implementation science, and health services research, the study team proposes to implement and evaluate via a randomized clinical trial the "TELE-TOC: Telehealth Education: Leveraging Electronic Transitions Of Care for COPD patients," intervention which includes a virtual visit, pharmacy-based, in-home intervention for COPD patients to improve medication use and patient outcomes among a population at high risk for readmission and medication safety events.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Telehealth Education Leveraging Electronic Transitions Of Care for COPD Patients (TELE-TOC): a study protocol for a type II hybrid effectiveness-implementation randomised, pragmatic clinical trial of a pharmacist-led intervention.
   Ramadurai D, Lee CT, Traeger L, Pucci G, et al · · 2025 · cited 1× · PMID 41193196 · DOI 10.1136/bmjopen-2025-105521