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NCT05897112

Comparative Efficacy of 10% Potassium Hydroxide Solution Versus Cryotherapy in Molluscum Contagiosum

Completed Phase 1 Last updated 9 June 2023
What this trial tests

Phase 1 trial testing Group A received cryotherpay in Molluscum Contagiosum in 60 participants. Completed in 30 April 2023.

Timeline
1 November 2022
Primary endpoint
30 April 2023
30 April 2023

Quick facts

Lead sponsorCombined Military Hospital Abbottabad
PhasePhase 1
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposetreatment
Enrollment60
Start date1 November 2022
Primary completion30 April 2023
Estimated completion30 April 2023
Sites1 location across Pakistan

Drugs / interventions tested

Conditions studied

Sponsor

Combined Military Hospital Abbottabad

Who can join

Adults 4 to 12, any sex, with Molluscum Contagiosum. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

A total of sixty patients presented to the outpatient dermatology department of Combined military hospital (CMH) Abbottabad with signs of molluscum contagiosum clinically diagnosed meeting inclusion criteria were enrolled. Sample size was calculated using WHO sample size calculator. They were divided into two groups i.e Group A and Group B using lottery method. Patients in Group A were subjected to cryotherapy (liquid nitrogen gas) whereas patients in Group B patients were subjected to 10% potassium hydroxide solution for 3 weeks and were followed up at 2nd, 4th, 8th and 12th week for observing the progress of therapy in both groups on each follow up visit and ascertaining the efficacy respectively.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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