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NCT05895773
Oro-nasal Decontamination to Prevent Ventilator-associated Pneumonia
Phase 2, PHASE3 trial testing Povidone-Iodine in Ventilator Associated Pneumonia in 78 participants. Completed in 24 November 2023.
24 November 2023
Quick facts
| Lead sponsor | Menoufia University |
|---|---|
| Phase | Phase 2, PHASE3 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | prevention |
| Enrollment | 78 |
| Start date | 24 June 2023 |
| Primary completion | 24 November 2023 |
| Estimated completion | 24 November 2023 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Povidone-Iodine — full drug profile →
- Saline spray
Conditions studied
- Ventilator Associated Pneumonia — all drugs for Ventilator Associated Pneumonia →
Sponsor
Menoufia University
Who can join
Adults 18 to 70, any sex, with Ventilator Associated Pneumonia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
It has been shown that oral hygiene reduces the incidence of ventilator-associated pneumonia (VAP). The nasopharynx is considered to be an important source of contaminated micro aspiration to the lung however, the effect of nasopharyngeal decontamination on VAP has not been yet investigated. The investigators hypothesized that decontamination of oral and nasopharyngeal cavities with combined Povidone Iodine and glycyrrhizin would remarkably reduce the incidence of VAP.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05895773
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Ventilator Associated Pneumonia
Currently open trials in the same condition.
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Other Menoufia University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05895773 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Menoufia University
- Last refreshed: 27 November 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05895773.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing