The Importance of Dopamine and Selected Polymorphisms Within the Genes of the Dopaminergic Pathway in Assessment of the Risk of Development and Severity of Sleep Breathing Disorders.

NCT05890911 ENROLLING_BY_INVITATION

The participants in the study will be adult patients with suspected sleep-disordered breathing. A one-night polysomnography will be performed using the NOXA1 device (NOX Medical, Reykjavík, Iceland). During the polysomnographic examination, sleep, breathing, heart rate and activity of the masticatory muscles will be recorded. Blood sample will be taken from each of the participants qualified to the study and control group to determine the level of dopamine and used to perform genetic tests of selected single nucleotide polymorphisms occurring within the genes regulating the concentration of dopamine and genes encoding dopamine receptors.

Details

Lead sponsor	Wroclaw Medical University
Status	ENROLLING_BY_INVITATION
Enrolment	100
Start date	2023-06-01
Completion	2026-12

Conditions

• Sleep Apnea
• Sleep-Disordered Breathing

Interventions

• Polysomnography
• Blood dopamine level measurement
• Genetical test

Primary outcomes

• Relationship between sleep-disordered breathing and blood dopamine level. — June 1, 2023 - December 31, 2023
  Each participant will undergo blood test focusing on the level of dopamine.

Countries

Poland