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NCT05887934

Bone-Lead Level Associations With Brain and Mental Health

ENROLLING BY INVITATION Last updated 14 October 2025
What this trial tests

trial testing X-Ray Fluorescence Analyzer in Lead Exposure in 500 participants. Enrolling by invitation.

Timeline
17 August 2023
Primary endpoint
1 May 2027
1 May 2027

Quick facts

Lead sponsorMedical University of South Carolina
StatusENROLLING BY INVITATION
Study typeOBSERVATIONAL
Enrollment500
Start date17 August 2023
Primary completion1 May 2027
Estimated completion1 May 2027
Sites1 location across United States

Drugs / interventions tested

Conditions studied

Sponsor

Medical University of South Carolina

Who can join

Adults 18 to 70, any sex, with Lead Exposure. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this study is to assess cumulative lead exposure among treatment-seeking patients in the MUSC hospital system receiving experimental transcranial magnetic stimulation (TMS), transcranial direct-current stimulation (tDCS), an electroencephalogram (EEG), and/or transcutaneous auricular vagus nerve stimulation (taVNS) therapies to determine whether lead exposure represents a risk factor for more severe mental illness or a modifier of treatment response. Information will be obtained from patients with a variety of neuropsychiatric disorders recruited to existing hospital studies. This information will include the results of bone-lead testing, brief cognitive tests, and self-reported psychiatric symptoms and behaviors.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other Medical University of South Carolina trials

Trials by the same sponsor.

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05887934.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing