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NCT05887011: PASSAT

CRT( Chemo-Radiation Therapy) Patterns and Short-term Outcomes on Unresectable NSCLC and SCLC in Routine Practices in Russia

Recruiting now Last updated 21 January 2026
What this trial tests

trial in Unresectable /Inoperable Locally Advanced (Stage II-III) NSCLC and Locally Advanced LS-SCLC (Stage I-III) in 2,000 participants. Currently enrolling.

Timeline
31 March 2023
Primary endpoint
30 June 2026
30 June 2026

Quick facts

Lead sponsorAstraZeneca
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment2,000
Start date31 March 2023
Primary completion30 June 2026
Estimated completion30 June 2026
Sites41 locations across Russia

Conditions studied

Sponsor

AstraZeneca — full company profile →

Who can join

18 and older, any sex, with Unresectable /Inoperable Locally Advanced (Stage II-III) NSCLC and Locally Advanced LS-SCLC (Stage I-III). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a multi-center, non-interventional, study with the aim to access routine practice of diagnostic and treatment approaches in patients with NSCLC and SCLC in 50 largest oncology centers in Russian Federation. The data for all 2000 patients with LA NSCLC and LS-SCLC who receiving CRT will have been collected for 2 years from the primary medical records. Demographic and clinical characteristics of the patients, information of routine diagnostics procedures and treatment approaches for patients with unresectable LA NSCLC and LS-SCLC and the treatment results of the end of CRT will be collected. Information about any specific NSCLC or SCLC treatments following CRT (e.g., durvalumab) will not be collected in the study. Patients with NSCLC and SCLC meeting the inclusion criteria will be prospectively enrolled into the study. Study procedures will comply with all the local regulatory requirements regarding AE reporting (pharmacovigilance). Study design considers secondary data collection approach using existing patients' medical records, after patients' visits according to routine sites' practice. Data for visit (record) 1 will be collected at the start of CRT (concurrent or sequential), and data for visit (record) 2 will be collected after the last dose of RT and with CT control results available, but the time frame for this data collection is expected to be no later than 6 months after visit 1.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Data sources for this page

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