Last reviewed · How we verify
NCT05886283
Qualitative and Quantitative Endothelium Changes After Cataract Surgery: Ultrasound Phacoemulsification vs Nanolaser Technique
NA trial testing phacoemulsification in Effect of Cataract Surgery on Corneal Endothelium; About 2 Techniques in 74 participants. Completed in 30 December 2020.
31 May 2020
Quick facts
| Lead sponsor | University Tunis El Manar |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 74 |
| Start date | 1 March 2017 |
| Primary completion | 31 May 2020 |
| Estimated completion | 30 December 2020 |
| Sites | 1 location across Tunisia |
Drugs / interventions tested
- phacoemulsification
- utrasound phacoemulsification
- nanolaser phacoemulsification
Conditions studied
- Effect of Cataract Surgery on Corneal Endothelium; About 2 Techniques — all drugs for Effect of Cataract Surgery on Corneal Endothelium; About 2 Techniques →
Sponsor
University Tunis El Manar
Who can join
Adults 50 to 90, any sex, with Effect of Cataract Surgery on Corneal Endothelium; About 2 Techniques. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Purpose: The aim of this study was to evaluate corneal endothelial cell density and morphology, central corneal thickness, and best visual acuity using US phacoemulsification or Nanosecond laser technique. Setting: Department of ophthalmology, Nabeul, Tunisia. Design: Prospective cohort study. Methods: The study included eyes with nuclear cataract density grade 1, 2, 3, or 4 according to LOCS III, divided into two groups; Group 1 had conventional US, and group 2 had nanosecond laser. The Endothelial Cell Density (ECD), coefficient of variation (CoV) in cell size, percentage of hexagonal cells, central corneal thickness and best visual acuity were evaluated over 24 months.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Qualitative and quantitative endothelium changes after cataract surgery: ultrasound phacoemulsification vs. nanolaser technique.
Zbiba W, Kharrat M, Sayadi S, Kallel Z, et al · · 2023 · PMID 37809334 · DOI 10.3389/fmed.2023.1097404
Verify or expand the search:
- PubMed search for NCT05886283
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of phacoemulsification
Trials testing the same drug.
- NCT06904560 — The Relation Between BSS Solution Temperature and Endothelial Cells and Post Phaco Discomfort · NA · not yet recruiting
- NCT07252154 — Modified Nuclear Phacoemulsification in Brown Cataract · NA · completed
- NCT06974578 — Capsular Tension Ring With Hydeophilic Intraocular Lesnes to Decrease Posterior Capsule Opacification Versus Hydrophobic · NA · completed
- NCT05871034 — Electroretinogram and Retinal Vascular Changes After Cataract Surgery · NA · unknown
- NCT06741774 — Efficacy and Safety of Trabecular Meshwork Microstent Drainage System ( MicroCOGO ) · NA · active not recruiting
Other University Tunis El Manar trials
Trials by the same sponsor.
- NCT07467967 — Impact of Date Consumption on Metabolic Control and Oxidative Stress in Patients With Type 2 Diabetes · NA · not yet recruiting
- NCT07378904 — Sterile Water Injection vs Morphine for Renal Colic · NA · active not recruiting
- NCT07313553 — Prevention of Rebound Pain After Axillary Block · NA · not yet recruiting
- NCT07240961 — Lumbal Erector Spinae Plane Block for Pain Management After Total Hip Arthroplasty · NA · recruiting
- NCT07194967 — Virtual Reality for Pain and Anxiety Relief in Labor · NA · enrolling by invitation
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05886283 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Tunis El Manar
- Last refreshed: 5 June 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05886283.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing