NCT05884229 is a NA clinical trial of Intra-operative analgesia guided by SPI in Intraoperative Monitoring, sponsored by Iuliu Hatieganu University of Medicine and Pharmacy.

Who is sponsoring NCT05884229?

NCT05884229 is sponsored by Iuliu Hatieganu University of Medicine and Pharmacy.

What drugs are being tested in NCT05884229?

Interventions in NCT05884229: Intra-operative analgesia guided by SPI.

What condition does NCT05884229 study?

NCT05884229 studies Intraoperative Monitoring.

Is NCT05884229 still recruiting?

NCT05884229 is currently status unknown. Last updated 1 June 2023.

Last reviewed 2023-06-01 · How we verify

NCT05884229

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effect of SPI (Surgical Pleth Index) - Guided Anaesthesia on Opioid Consumption in Gastric Sleeve Surgery

Status unknown NA Last updated 1 June 2023

What this trial tests

NA trial testing Intra-operative analgesia guided by SPI in Intraoperative Monitoring in 40 participants. Status unknown.

Timeline

1 January 2023

Primary endpoint
1 January 2024

1 January 2024

Quick facts

Lead sponsor	Iuliu Hatieganu University of Medicine and Pharmacy
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	other
Enrollment	40
Start date	1 January 2023
Primary completion	1 January 2024
Estimated completion	1 January 2024
Sites	1 location across Romania

Drugs / interventions tested

Intra-operative analgesia guided by SPI

Conditions studied

Intraoperative Monitoring — all drugs for Intraoperative Monitoring →

Sponsor

Iuliu Hatieganu University of Medicine and Pharmacy

Who can join

Adults 18 to 65, any sex, with Intraoperative Monitoring. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a unicentric, prospective randomised trial that aims to evaluate the role of intra-operative monitoring of nociception through SPI (Surgical Pleth Index) in guiding analgesia and reducing opioid consumption in obese patients undergoing bariatric surgery. We aim to enrol 40 patients having laparoscopic gastric sleeve surgery in the Cluj-Napoca County Hospital. They will be randomised into two groups, one with opioid administration during surgery guided by SPI, and the other one guided by anesthetist experience. We will monitor opioid consumption, pain scores during the first 90 minutes post-operatively, hemodinamic events during surgery and the duration between reversal of neuromuscular block and extubation.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Influence of Surgical Pleth Index-Guided Versus Conventional Analgesia on Opioid Consumption During Gastric Sleeve Surgery: A Pilot Study.
Leahu CE, Petrisor C, Cocu S, Boldis AM, et al · · 2025 · PMID 41157243 · DOI 10.3390/life15101570

Verify or expand the search:

Other recruiting trials for Intraoperative Monitoring

Currently open trials in the same condition.

NCT07280546 — Analysis of Breath Sounds During Surgery · recruiting
NCT07442214 — View of Cerebral Perfusion in Liver Transplantation · active not recruiting

Other Iuliu Hatieganu University of Medicine and Pharmacy trials

Trials by the same sponsor.

NCT07397091 — Using Routine Inflammatory and Metabolic Blood Tests (Bedside Included) to Predict Brain Injury in Children After Minor · not yet recruiting
NCT07362173 — Actualities in Procedural Sedation: Remimazolam · Phase 4 · active not recruiting
NCT06771999 — Attitudes Towards Deprescribing Medications in Cancer Patients and Impact of Educational Intervention by a Clinical Phar · NA · recruiting
NCT06251869 — Electrocoagulation vs. Cold Knife Cutting in Joint Arthroplasty (Electrocoagulation vs Scalpel) · recruiting
NCT06283836 — Dexmedetomidine vs. Remifentanil Conscious Sedation for Stapedotomy/Stapedectomy · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05884229 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Iuliu Hatieganu University of Medicine and Pharmacy
Last refreshed: 1 June 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05884229.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing