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NCT05884099: CRYO-VATS-2
Intercostal Cryoanalgesia for Chronic Pain After VATS Lung Resection
NA trial testing Cryoanalgesia AND single-injection paravertebral block in Cryotherapy Effect in 80 participants. Completed in 21 April 2025.
21 January 2025
Quick facts
| Lead sponsor | Centre hospitalier de l'Université de Montréal (CHUM) |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 80 |
| Start date | 9 November 2023 |
| Primary completion | 21 January 2025 |
| Estimated completion | 21 April 2025 |
| Sites | 1 location across Canada |
Drugs / interventions tested
- Cryoanalgesia AND single-injection paravertebral block
- Single-injection paravertebral block
Conditions studied
- Cryotherapy Effect — all drugs for Cryotherapy Effect →
- Chronic Pain — all drugs for Chronic Pain →
- Lung Cancer — all drugs for Lung Cancer →
- Surgery — all drugs for Surgery →
Sponsor
Centre hospitalier de l'Université de Montréal (CHUM)
Who can join
18 and older, any sex, with Cryotherapy Effect or Chronic Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Intercostal cryoanalgesia is a technique that allows extensive and prolonged analgesia of the hemithorax. The aim of this study is to demonstrate the efficacy of intercostal cryoanalgesia as an adjunct to a single-injection paravertebral block for the prevention of chronic thoracic pain after VATS lung resection surgery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05884099
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Cryoanalgesia AND single-injection paravertebral block
Trials testing the same drug.
- NCT05896150 — Intercostal Cryoanalgesia for Acute Pain After VATS Lung Resection · NA · completed
Other recruiting trials for Cryotherapy Effect
Currently open trials in the same condition.
- NCT06939374 — Intracoronary Cryotherapy Effect on Stabilization of Vulnerable Plaque in Patients With Stable Angina or ACS - A Traditi · NA · recruiting
- NCT06356831 — National Registry of Surgical Treatment and Percutaneous Cryoablation of Parietal Endometriosis · recruiting
- NCT05692427 — Evaluation of Cryotherapy in Granuloma Pyogenicum · NA · recruiting
- NCT05600088 — Intracoronary Cryotherapy Effect on Stabilization of Vulnerable Plaque in Patients With (N)STEMI or Unstable Angina · NA · active not recruiting
- NCT05348447 — Intercostal Nerve Cryotherapy in Patients Undergoing Minimally Invasive Pulmonary Resection · NA · active not recruiting
Other Centre hospitalier de l'Université de Montréal (CHUM) trials
Trials by the same sponsor.
- NCT06735638 — Outside the Cage (OTC) Robotic Esophagectomy · Phase 1 · not yet recruiting
- NCT07533253 — Rescue Distal Thrombectomy in Treatment for Persistent Distal Occlusions · NA · not yet recruiting
- NCT05225272 — Effectiveness of an Enhanced Recovery After Surgery Protocol in Patients Undergoing On-pump Cardiac Surgery · not yet recruiting
- NCT07497061 — Comparison of Two Surgical Techniques for the Treatment of Trigger Fingers: Longitudinal Opening Versus Complete A1 Pull · NA · not yet recruiting
- NCT07196410 — KAN-004 for Immune-Related Diarrhea or Colitis · Phase 1 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05884099 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Centre hospitalier de l'Université de Montréal (CHUM)
- Last refreshed: 4 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05884099.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing