NCT05883800 (TNT-RECORD) is a NA clinical trial of On-couch adaptive radiotherapy in Rectal Cancer, sponsored by Haukeland University Hospital.

Who is sponsoring NCT05883800?

NCT05883800 is sponsored by Haukeland University Hospital.

What drugs are being tested in NCT05883800?

Interventions in NCT05883800: On-couch adaptive radiotherapy.

What condition does NCT05883800 study?

NCT05883800 studies Rectal Cancer.

Is NCT05883800 still recruiting?

NCT05883800 is currently recruiting now. Last updated 19 March 2024.

Last reviewed 2024-03-19 · How we verify

NCT05883800: TNT-RECORD

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Total Neoadjuvant Treatment Combined With Adaptive Radiotherapy for Rectal Cancer

Recruiting now NA Last updated 19 March 2024

What this trial tests

NA trial testing On-couch adaptive radiotherapy in Rectal Cancer in 61 participants. Currently enrolling.

Timeline

22 June 2023

Primary endpoint
31 December 2026

31 December 2031

Quick facts

Lead sponsor	Haukeland University Hospital
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	treatment
Enrollment	61
Start date	22 June 2023
Primary completion	31 December 2026
Estimated completion	31 December 2031
Sites	1 location across Norway

Drugs / interventions tested

On-couch adaptive radiotherapy

Conditions studied

Rectal Cancer — all drugs for Rectal Cancer →

Sponsor

Haukeland University Hospital

Who can join

18 and older, any sex, with Rectal Cancer. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Diarrhea was the most frequently reported severe adverse event in the treatment regime of pre-operative sequential short-course radiotherapy followed by chemotherapy (so called total neo-adjuvant treatment). This study therefore investigates the benefit of on-couch adaptation for locally advanced rectal cancer patients undergoing this treatment regime.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Comparing robust proton versus online adaptive photon radiotherapy for short-course treatment of rectal cancer.
Hundvin JA, Hege Lilleøren U, Valdman A, Sorcini B, et al · · 2024 · PMID 39559486 · DOI 10.1016/j.phro.2024.100663

Verify or expand the search:

Other recruiting trials for Rectal Cancer

Currently open trials in the same condition.

NCT07528209 — Neoadjuvant CAPOX With or Without Pucotenlimab Plus Selective Radiotherapy for Locally Advanced Rectal Cancer · Phase 3 · recruiting
NCT07537998 — Antegrade Intestinal Fluid Reinfusion for Prevention of Low Anterior Resection Syndrome After Low Anterior Resection: a · Phase 2, PHASE3 · recruiting
NCT07501845 — Registry Maastro Applicator · recruiting
NCT07369531 — The Impact of Two-Stage Turnbull-Cutait Pull-Through Coloanal Anastomosis on Stoma-free Survival in Low Rectal Anal-pres · NA · recruiting
NCT07505472 — Efficacy and Safety Comparison of Short-course Radiotherapy Followed by CapeOX Chemotherapy Plus Toripalimab With or Wit · Phase 2, PHASE3 · recruiting

Other Haukeland University Hospital trials

Trials by the same sponsor.

NCT07450105 — Intensive Dialectical Behavior Therapy for Self-Harm and Suicidal Behavior in Youth: A Pilot Study · NA · not yet recruiting
NCT07450092 — Prehospital Use of Forced Air Warming · NA · enrolling by invitation
NCT07268716 — Assess the Efficacy of Tailored Patient Information and Voluntary Patient-managed Outpatient Digital Follow-up (I-POD) a · NA · not yet recruiting
NCT07392697 — The Intravenous Amino Acid Therapy for Vascular Rigidity in End Stage Renal Disease · NA · not yet recruiting
NCT07304219 — Physical Activity Based Treatment for Youth With Depression and Anxiety · NA · enrolling by invitation

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05883800 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Haukeland University Hospital
Last refreshed: 19 March 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05883800.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing