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NCT05882396

Rood's Approach and Oxaliplatin-induced Peripheral Neuropathy in Colorectal Cancer Patients

Status unknown NA Last updated 31 May 2023
What this trial tests

NA trial testing Rood's approach in Colorectal Cancer in 60 participants. Status unknown.

Timeline
1 June 2023
Primary endpoint
28 December 2023
11 January 2024

Quick facts

Lead sponsorCairo University
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingnone
Primary purposetreatment
Enrollment60
Start date1 June 2023
Primary completion28 December 2023
Estimated completion11 January 2024

Drugs / interventions tested

Conditions studied

Sponsor

Cairo University

Who can join

Adults 18 to 60, any sex, with Colorectal Cancer or Peripheral Neuropathy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Oxaliplatin-induced chronic peripheral neuropathy is of major concern to oncologists and patients as it has been shown to affect patients' health-related quality of life. Although a number of interventions have been implicated, none of them can be recommended for clinical use. This therapeutic failure reflects a poor understanding of the real mechanism of oxaliplatin-induced neuropathy. However, oxidative stress is identified to be one of the main biomolecular dysfunctions in this neuropathy. Rood's approach is a neurophysiological approach that is based on reflexes of the central nervous system in which the sensory stimulation provides desired muscular response and was specially designed for patients with motor control problems. It was developed by Margeret Rood in 1940. According to Rood, sensory stimulation can activate or deactivate the receptor by facilitation or inhibition, which makes it possible to get the desired muscular response.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Colorectal Cancer

Currently open trials in the same condition.

Other Cairo University trials

Trials by the same sponsor.

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Data sources for this page

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