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NCT05881252
Perinatal Outcomes Following Change in Clinical Criteria in for Treatment of Maternal Hypertension
trial testing Clinical blood pressure threshold of SBP >= 160 mmHg for acute treatment of hypertension in Maternal Hypertension in 1,003 participants. Completed in 4 April 2024.
4 April 2024
Quick facts
| Lead sponsor | The University of Texas Health Science Center, Houston |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 1,003 |
| Start date | 11 May 2023 |
| Primary completion | 4 April 2024 |
| Estimated completion | 4 April 2024 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Clinical blood pressure threshold of SBP >= 160 mmHg for acute treatment of hypertension
- Clinical blood pressure threshold of SBP >= 180 mmHg for acute treatment of hypertension
Conditions studied
- Maternal Hypertension — all drugs for Maternal Hypertension →
Sponsor
The University of Texas Health Science Center, Houston
Who can join
Eligibility, female only, with Maternal Hypertension. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is observe outcomes before and after a change in clinical practice in the threshold for management of severe hypertension in pregnancy and the post-partum period. Outcomes will be observed for 10 months under the current (traditional) clinical blood pressure threshold for acute treatment of hypertension, which is \>= 160 millimeters of mercury (mmHg) systolic blood pressure (SBP). This will be followed by one month of education about rationale for the new SBP threshold of \>= 180 mmHg and change of clinical guidelines. Then, there will be 10 months of observation after adopting the updated clinical threshold for acute antihypertensive treatment (\>= 180 SBP).
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05881252
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05881252 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The University of Texas Health Science Center, Houston
- Last refreshed: 28 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05881252.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing