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NCT05880732
Magnesium Sulfate on Postoperative Pain
NA trial testing Magnesium Sulfate in Postoperative Pain in 68 participants. Completed in 1 March 2022.
1 January 2022
Quick facts
| Lead sponsor | Pamukkale University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 68 |
| Start date | 1 January 2021 |
| Primary completion | 1 January 2022 |
| Estimated completion | 1 March 2022 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Magnesium Sulfate — full drug profile →
- normal saline isotonic solution — full drug profile →
Conditions studied
- Postoperative Pain — all drugs for Postoperative Pain →
Sponsor
Pamukkale University
Who can join
18 and older, female only, with Postoperative Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Breast cancer is the most diagnosed type of cancer in women in Turkey and in the world. According to the World Health Organization data, the rate of newly diagnosed breast cancer was reported as 11.6% in 20181. Acute postoperative pain occurs in 40% of patients undergoing surgery for breast cancer2. In the early postoperative period, opioids are commonly used analgesics in the treatment of pain, but they have various side effects such as gastrointestinal, urinary and respiratory symptoms3. Non-opioid analgesics can be used to reduce opioid use and thus limit its side effects. Magnesium sulfate (MgSO4) is an N-Methyl D-Aspartate (NMDA) receptor antagonist that has been used for postoperative analgesia and reducing both the duration and intensity of pain by preventing central sensitization in response to peripheral painful stimulus4-9. The primary aim of this study is to investigate the postoperative analgesic efficacy of MgSO4 in patients who were scheduled for mastectomy with the diagnosis of breast cancer. The secondary aim of our study is to evaluate the changes in perioperative vital signs that may occur due to MgSO4.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05880732
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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- Google Scholar
Related trials
Other trials of Magnesium Sulfate
Trials testing the same drug.
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- NCT06455514 — Post-CA Neuroprotection With Magnesium · Phase 1 · recruiting
- NCT06131905 — Magnesium Sulfate as an Adjuvant to Propofol During Consious Sedation in Colonoscopy · Phase 2, PHASE3 · unknown
- NCT05343806 — Nifedipine Versus Magnesium Sulfate for Late Preterm Tocolysis · NA · unknown
Other recruiting trials for Postoperative Pain
Currently open trials in the same condition.
- NCT07452120 — DIPB vs. SIFIB for Postoperative Analgesia After Hip Surgery · NA · recruiting
- NCT07396688 — Comparative Evaluation of the Effects of Calcium Hydroxide and BIO-C Temp Medicaments on Postoperative Pain in Patients · NA · recruiting
- NCT07413055 — Comparative Efficacy Of 4 mg VS. 8 mg Submucosal Dexamethasone In Postoperative Pain Management After Dental Implant Sur · Phase 3 · recruiting
- NCT07496086 — External Oblique Intercostal Block Versus Transversus Abdominis Plane Combined With Rectus Sheath Block on Postoperative · NA · recruiting
- NCT07396545 — External Oblique Intercostal Block Versus Erector Spinae Plane Block on Postoperative Pain in Laparoscopic Radical Gastr · NA · recruiting
Other Pamukkale University trials
Trials by the same sponsor.
- NCT06667856 — Foot Core Exercise Training With Telerehabilitation · NA · suspended
- NCT07532499 — EMG-Triggered Electrical Stimulation After Median/Ulnar Nerve Repairs · NA · not yet recruiting
- NCT07473232 — Comparison of Platelet-rich Plasma and Activated Cytokine-rich Serum Injection Treatments in Patients With Knee Osteoart · NA · not yet recruiting
- NCT07520084 — Predictors of Climate Change Health Literacy in Older Individuals · recruiting
- NCT07388316 — Functional Improvement and Fine Dexterity in Thumb Tendon Injuries · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05880732 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Pamukkale University
- Last refreshed: 30 May 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05880732.
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