Last reviewed · How we verify
NCT05877144
LiSWT for Nerve Sparing Radical Prostatectomy ED
NA trial testing Nerve-Sparing Prostatectomy in Erectile Dysfunction in 8 participants. Completed in 30 January 2025.
30 January 2025
Quick facts
| Lead sponsor | Thomas Jefferson University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 8 |
| Start date | 6 July 2023 |
| Primary completion | 30 January 2025 |
| Estimated completion | 30 January 2025 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Nerve-Sparing Prostatectomy
- Medical Device Usage and Evaluation
- Duplex Ultrasound
- Survey Administration
- Nerve-Sparing Prostatectomy
- Sham Intervention
- Duplex Ultrasound
- Survey Administration
Conditions studied
- Erectile Dysfunction — all drugs for Erectile Dysfunction →
- Localized Prostate Carcinoma — all drugs for Localized Prostate Carcinoma →
- Stage I Prostate Cancer AJCC v8 — all drugs for Stage I Prostate Cancer AJCC v8 →
- Stage II Prostate Cancer AJCC v8 — all drugs for Stage II Prostate Cancer AJCC v8 →
Sponsor
Thomas Jefferson University
Who can join
Adults 18 to 80, male only, with Erectile Dysfunction or Localized Prostate Carcinoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This phase I clinical trial studies how well low intensity shockwave therapy (LiSWT) improves erectile function in patients who have had nerve-sparing radical prostatectomy (NS-RP), a type of surgery that attempts to save the nerves near the tissues being removed, for prostate cancer. Erectile dysfunction (ED) is a known side effect of the radical prostatectomy procedure. The low intensity shockwave therapy delivers painless electrotherapy pulse to increase blood flow and supply, activation of tissues and wound healing. Using LiSWT after NS-PRP may improve erectile function in men with prostate cancer.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05877144
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Thomas Jefferson University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05877144 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Thomas Jefferson University
- Last refreshed: 15 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05877144.
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