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NCT05876455
Comparative Evaluation of Minimally Invasive Nonsurgical Periodontal Therapy Versus Conventional Subgingival Instrumentation
NA trial testing Conventional Subgingival Instrumentation in Periodontitis in 20 participants. Status unknown.
10 October 2023
Quick facts
| Lead sponsor | Postgraduate Institute of Dental Sciences Rohtak |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 10 July 2023 |
| Primary completion | 10 October 2023 |
| Estimated completion | 10 November 2023 |
| Sites | 1 location across India |
Drugs / interventions tested
- Conventional Subgingival Instrumentation
- minimally invasive non-surgical periodontal therapy
Conditions studied
- Periodontitis — all drugs for Periodontitis →
- Subgingival Plaque — all drugs for Subgingival Plaque →
Sponsor
Postgraduate Institute of Dental Sciences Rohtak
Who can join
Adults 18 to 50, any sex, with Periodontitis or Subgingival Plaque. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Background- The use of minimally invasive procedures has recently been advocated for the treatment of periodontitis, to minimize patient discomfort and maximize the healing potential. These techniques usually involve the use of magnification lenses or microscopes and small instruments which reduce the risk of tissue trauma compared with traditional instruments. Rationale- So far only descriptive data about the clinical effects of such procedure are available and comparative studies that would include other treatment alternatives are lacking. Therefore, the aim of this study is, on split-mouth model, to compare the number of diseased sites (defined by probing depth ˃ 4 mm and bleeding on probing) after conventional subgingival instrumentation and Minimally invasive nonsurgical periodontal therapy (MINST) with the usage of special mini instruments and magnifying loupes. Objectives- To compare sites that have residual probing depth and require further surgical intervention after undergoing the two treatment modalities. Methods- In this split mouth randomized controlled trial, Test group will undergo non surgical therapy under magnification and using special mini bladed instruments while the control group will undergo conventional subgingival instrumentation. Reevaluation will be at 6 weeks and 3 months. Expected outcomes- If both the groups differ in outcomes after therapy, MINST can be used to minimize the number of sites that require surgery and hence will reduce treatment costs and morbidity.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT05876455
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05876455 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Postgraduate Institute of Dental Sciences Rohtak
- Last refreshed: 25 May 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05876455.
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