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NCT05874531
End-expiratory Occlusion Test and Prediction of Preload Dependence
trial testing End-expiratory occlusion test in Intensive Care Units in 60 participants. Completed in 15 September 2023.
15 August 2023
Quick facts
| Lead sponsor | Mongi Slim Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 60 |
| Start date | 15 May 2023 |
| Primary completion | 15 August 2023 |
| Estimated completion | 15 September 2023 |
| Sites | 1 location across Tunisia |
Drugs / interventions tested
- End-expiratory occlusion test
Conditions studied
- Intensive Care Units — all drugs for Intensive Care Units →
- Ultrasonography — all drugs for Ultrasonography →
- Blood Volume — all drugs for Blood Volume →
Sponsor
Mongi Slim Hospital
Who can join
18 and older, any sex, with Intensive Care Units or Ultrasonography. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Three sets of measurements of hemodynamic parameters and sub-aortic VTI were performed: before and at the end of 15 seconds end-expiratory occlusion and after 250 mL saline administration over 10 minutes. Patients were considered responders to fluid loading after an increase in sub-aortic VTI of more than 10% following a volume expansion. SPSS was used for statistic study. A p \< 0.05 was considered significant. The investigators performed univariate and then multivariate analysis.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05874531
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Related trials
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Trials testing the same drug.
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Other Mongi Slim Hospital trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05874531 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mongi Slim Hospital
- Last refreshed: 25 September 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05874531.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing