NCT05872113

Evaluation of Human Efficacy for Skin Moisturization and Wrinkle Improvement

Completed NA Last updated 24 May 2023

What this trial tests

NA trial testing Hs-hWE cream in Dry Skin in 22 participants. Completed in 16 November 2021.

Timeline

1 October 2021

Primary endpoint
5 November 2021

16 November 2021

Quick facts

Lead sponsor	Ji Hye Yoon
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	single group
Masking	single
Primary purpose	basic science
Enrollment	22
Start date	1 October 2021
Primary completion	5 November 2021
Estimated completion	16 November 2021
Sites	1 location across South Korea

Drugs / interventions tested

• Hs-hWE cream
• Placebo cream

Conditions studied

• Dry Skin — all drugs for Dry Skin →

Sponsor

Ji Hye Yoon

Who can join

Adults 30 to 59, female only, with Dry Skin. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

All subjects used the placebo sample on the left side of their face and the investigational sample on the right side of their face, respectively. The moisturizing levels were detected before use (0 week), after 2 weeks and after 4 weeks. The wrinkles of subjects were also measured on the same date interval as the skin moisture level test.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. <i>Hydrangea serrata</i> Hot Water Extract and Its Major Ingredient Hydrangenol Improve Skin Moisturization and Wrinkle Conditions via AP-1 and Akt/PI3K Pathway Upregulation.
   Yoon JH, Park SH, Yoon SE, Hong SY, et al · · 2023 · cited 5× · PMID 37299400 · DOI 10.3390/nu15112436