NCT05870774 is a NA clinical trial of Soft tissue augmentation with CTG in Soft Tissue Atrophy, sponsored by I.M. Sechenov First Moscow State Medical University.

Who is sponsoring NCT05870774?

NCT05870774 is sponsored by I.M. Sechenov First Moscow State Medical University.

What drugs are being tested in NCT05870774?

Interventions in NCT05870774: Soft tissue augmentation with CTG, Soft tissue augmentation with CM.

What condition does NCT05870774 study?

NCT05870774 studies Soft Tissue Atrophy.

Is NCT05870774 still recruiting?

NCT05870774 is currently completed. Last updated 26 September 2025.

Last reviewed 2025-09-26 · How we verify

NCT05870774

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Comparative Analysis Using the Collagen Matrix and Autogenous Graft: Clinical Course, Aesthetic Results

Completed NA Last updated 26 September 2025

What this trial tests

NA trial testing Soft tissue augmentation with CTG in Soft Tissue Atrophy in 52 participants. Completed in 18 May 2023.

Timeline

28 October 2021

Primary endpoint
25 December 2022

18 May 2023

Quick facts

Lead sponsor	I.M. Sechenov First Moscow State Medical University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	52
Start date	28 October 2021
Primary completion	25 December 2022
Estimated completion	18 May 2023
Sites	1 location across Russia

Drugs / interventions tested

Soft tissue augmentation with CTG
Soft tissue augmentation with CM

Conditions studied

Soft Tissue Atrophy — all drugs for Soft Tissue Atrophy →

Sponsor

I.M. Sechenov First Moscow State Medical University

Who can join

Adults 25 to 59, any sex, with Soft Tissue Atrophy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This was an interventional prospective randomized clinical trial (RCT) in parallel groups. The sample size is 32 patients who were randomly divided into two groups depending on the surgical intervention used. First group - patients underwent increasing the thickness of the mucous membrane using free connective tissue graft from tuberosity area of the upper jaw. Second group - patients used collagen matrix Fibro-Gide" (Geistlich Pharma AG, Bahnhofstrasse 40, 6110 Wolhusen, Switzerland; registration in Russia 19.08.2020 No FSZ -20207/11765). In the postoperative period the value of soft tissue thickness gain, severity of pain, collateral edema, amount of analgesics consumed, soft tissue aesthetics, keratinized mucosa width, quality of life and duration of surgery were assessed.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

3D-Analysis of Peri-Implant Soft Tissue Gain With Collagen Matrix and Connective Tissue Graft: A Randomized Control Trial.
Ashurko I, Tarasenko S, Magdalyanova M, Balyasin M, et al · · 2025 · cited 1× · PMID 40254798 · DOI 10.1111/cid.70043

Verify or expand the search:

Other trials of Soft tissue augmentation with CTG

Trials testing the same drug.

NCT05551962 — Increasing the Thickness of Soft Tissues in the Esthetic Zone Around Implants · NA · unknown

Other recruiting trials for Soft Tissue Atrophy

Currently open trials in the same condition.

NCT04766255 — Behavioral Comparison of Three Different Graft Materials to Increase Soft Tissue Thickness Around Dental Implants. · Phase 4 · recruiting

Other I.M. Sechenov First Moscow State Medical University trials

Trials by the same sponsor.

NCT07348991 — Predicting Severe Cardiac Arrhythmias in the Perioperative Period Using AI-ECG · not yet recruiting
NCT07412457 — Guideline Adherence in Dyslipidemia With Clinical Decision Support · not yet recruiting
NCT07396792 — Screening for Cardiac and Cardiac-associated Pathology Using Single-channel Electrocardiogram · not yet recruiting
NCT07412418 — Screening for Pulmonary Embolism Using Single-channel Electrocardiogram · not yet recruiting
NCT07518550 — Maternal and Fetal Electrocardiograms Separation Algorithm · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05870774 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by I.M. Sechenov First Moscow State Medical University
Last refreshed: 26 September 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05870774.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing