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NCT05869123
Online Adaptive Radiotherapy for Postoperative Treatment of Endometrial and Cervical Cancer
Phase 1, PHASE2 trial testing Online adaptive radiotherapy in Uterine Cervical Neoplasm in 17 participants. Participants enrolled and being followed up; not accepting new ones.
3 March 2023
Quick facts
| Lead sponsor | Peking Union Medical College Hospital |
|---|---|
| Phase | Phase 1, PHASE2 |
| Status | Active, enrolled |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 17 |
| Start date | 20 October 2022 |
| Primary completion | 3 March 2023 |
| Estimated completion | 3 March 2025 |
| Sites | 1 location across China |
Drugs / interventions tested
- Online adaptive radiotherapy
Conditions studied
- Uterine Cervical Neoplasm — all drugs for Uterine Cervical Neoplasm →
- Endometrial Neoplasms — all drugs for Endometrial Neoplasms →
Sponsor
Peking Union Medical College Hospital
Who can join
Adults 18 to 70, female only, with Uterine Cervical Neoplasm or Endometrial Neoplasms. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Online adaptive radiotherapy (oART) has demonstrated to be feasible to reduce planning target volume (PTV) margins for postoperative treatment of endometrial and cervical cancer. To explore the value of reduced margins in oART for postoperative treatment of endometrial and cervical cancer, we conducted a prospective clinical trial to determine the clinical efficacy and toxicity of reduced margins.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Prospects for daily online adaptive radiotherapy for cervical cancer: Auto-contouring evaluation and dosimetric outcomes.
Zhang Y, Wang G, Chang Y, Wang Z, et al · · 2024 · cited 8× · PMID 38212767 · DOI 10.1186/s13014-024-02398-6
Verify or expand the search:
- PubMed search for NCT05869123
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Online adaptive radiotherapy
Trials testing the same drug.
- NCT05727553 — Implementation of Online Adaptive Radiotherapy for Breast Cancer Patients on Ethos (BREAST-ART) · unknown
Other recruiting trials for Uterine Cervical Neoplasm
Currently open trials in the same condition.
- NCT06560697 — Cervical Boost by Ablative Stereotactic Radiotherapy (SABR) vs Brachytherapy in Patients With Cervical Carcinoma · NA · recruiting
- NCT06598176 — Developing a Combined Molecular Screening and Triage Test for Cervical Cancer in Self-samples · NA · recruiting
- NCT04516616 — Pd-1 Antibody Combined Neoadjuvant Chemotherapy for Locally Advanced Cervical Cancer · Phase 2 · active not recruiting
- NCT04061967 — Research Project on Reminders and Self-Sampling Can Increase Participation in Gynecology Cell Sampling - Preventive Exam · NA · recruiting
- NCT03955185 — Clinical Trial of Minimally Invasive Surgery Versus Abdominal Surgery in Patients With Early Stage Cervical Cancer · NA · active not recruiting
Other Peking Union Medical College Hospital trials
Trials by the same sponsor.
- NCT07466251 — PCSK9 Inhibitor for Intracranial Atherosclerosis Related Acute Ischemic Stroke · Phase 4 · not yet recruiting
- NCT06743321 — Speech-to-speech Voice-cloning Care (SVCC) to Improve ICU-acquired Anxiety for Critically Ill Patients · NA · not yet recruiting
- NCT07590336 — 68Ga-NYM207 PET/CT Imaging in Hepatocellular Carcinoma · Phase 1, PHASE2 · not yet recruiting
- NCT07515976 — Mapping of Genomic Structural Variations in Major Birth Defects · not yet recruiting
- NCT07386756 — Early Precise Identification and Intervention Strategies for Individuals at High Risk of Prediabetes · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05869123 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Peking Union Medical College Hospital
- Last refreshed: 21 November 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05869123.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing