Who is sponsoring iNOCAPA?

iNOCAPA is sponsored by The Hospital for Sick Children.

What condition does iNOCAPA study?

iNOCAPA studies Cardiac Arrest.

What drugs are being tested in iNOCAPA?

Interventions: inhaled nitric oxide (iNO), Sham.

Last reviewed 2023-11-30 · How we verify

Inhaled Nitric Oxide for Cardiac Arrest in Pediatrics and Adults (iNOCAPA)

NCT05868109 PHASE2 UNKNOWN

This study is a multi-center, double blind, randomized controlled trial of inhaled nitric oxide (iNO) in children and adults with cardiac arrest (CA). The purpose of this pilot study is to test the feasibility of rapidly randomizing patients to iNO or sham treatment during cardiopulmonary resuscitation (CPR) or shortly after return of circulation (ROC) and evaluate blood biomarkers associated with iNO compared to sham. Return of circulation may refer to return of spontaneous circulation (ROSC) or ROC through extracorporeal cardiopulmonary resuscitation (E-CPR).

Details

Lead sponsor	The Hospital for Sick Children
Phase	PHASE2
Status	UNKNOWN
Enrolment	40
Start date	Wed Aug 31 2022 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Sat Jan 31 2026 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Cardiac Arrest

Interventions

inhaled nitric oxide (iNO)
Sham

Countries

Canada