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NCT05866497
Arterial Stiffness in Type 2 Diabetic Patients With Severe Periodontitis
trial testing clinical periodontal measurements in Coronary Heart Disease in 136 participants. Completed in 21 January 2023.
21 January 2023
Quick facts
| Lead sponsor | Pamukkale University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 136 |
| Start date | 10 June 2022 |
| Primary completion | 21 January 2023 |
| Estimated completion | 21 January 2023 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- clinical periodontal measurements
- CAVI measurements
Conditions studied
- Coronary Heart Disease — all drugs for Coronary Heart Disease →
- Diabetes Mellitus, Type 2 — all drugs for Diabetes Mellitus, Type 2 →
- Periodontitis — all drugs for Periodontitis →
- Arterial Stiffness — all drugs for Arterial Stiffness →
Sponsor
Pamukkale University
Who can join
Adults 20 to 70, any sex, with Coronary Heart Disease or Diabetes Mellitus, Type 2. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Studies were found that a significant relationship between the severe periodontitis and increased CAVI values. While the exact mechanisms linking periodontitis, type 2 diabetes, and cardiovascular disease are not yet fully understood, it is clear that these diseases are interconnected. There are limited data in the literature evaluating the risk of atherosclerosis in diabetic individuals with periodontal disease. In our survey, we hypothesised that severe periodontitis may be a risk factor for the development of subclinical atherosclerosis among people with type 2 diabetes. Thus, we aimed to investigate the potential risk of subclinical atherosclerosis by using a new surrogate marker CAVI in severe periodontitis patients with short-term diabetes.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT05866497
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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Other Pamukkale University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05866497 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Pamukkale University
- Last refreshed: 19 May 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05866497.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing