NCT05865275 is a NA clinical trial of Low-level laser treatment in Tooth Sensitivity, sponsored by University of Campania Luigi Vanvitelli.

Who is sponsoring NCT05865275?

NCT05865275 is sponsored by University of Campania Luigi Vanvitelli.

What drugs are being tested in NCT05865275?

Interventions in NCT05865275: Low-level laser treatment, tooth bleaching procedure.

What condition does NCT05865275 study?

NCT05865275 studies Tooth Sensitivity.

Is NCT05865275 still recruiting?

NCT05865275 is currently completed. Last updated 22 May 2023.

Last reviewed 2023-05-22 · How we verify

NCT05865275

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Diode Low-power Laser Before In-office Bleaching

Completed NA Last updated 22 May 2023

What this trial tests

NA trial testing Low-level laser treatment in Tooth Sensitivity in 30 participants. Completed in 20 December 2022.

Timeline

9 November 2021

Primary endpoint
13 December 2022

20 December 2022

Quick facts

Lead sponsor	University of Campania Luigi Vanvitelli
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	prevention
Enrollment	30
Start date	9 November 2021
Primary completion	13 December 2022
Estimated completion	20 December 2022
Sites	1 location across Italy

Drugs / interventions tested

Low-level laser treatment
tooth bleaching procedure

Conditions studied

Tooth Sensitivity — all drugs for Tooth Sensitivity →

Sponsor

University of Campania Luigi Vanvitelli

Who can join

18 and older, any sex, with Tooth Sensitivity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Background: The aim of study was to investigate the effectiveness of low-level laser therapy (LLLT) use before in-office bleaching to prevent risk and intensity of tooth sensitivity. Methods: thirty patients were selected for this clinical trial. Before bleaching procedures with 38 % hydrogen peroxide, the participants were randomly divided into two groups of 15 subjects. Test group: the patients teeth received a preliminary LLLT procedure by an 810 nm diode laser with 0.5 Watt for 30 s for an energy density of 15 J/cm2 and a group placebo: the patients received the same preliminary LLLT but with the device switch off. All patients were instructed to report their cold sensitivity experiences immediately, 1 h, 24 h, and 48 h after the end of bleaching by a visual analog scale score between 0-10.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The Use of Diode Low-Power Laser Therapy before In-Office Bleaching to Prevent Bleaching-Induced Tooth Sensitivity: A Clinical Double-Blind Randomized Study.
Femiano F, Femiano R, Scotti N, Nucci L, et al · · 2023 · cited 3× · PMID 37504242 · DOI 10.3390/dj11070176

Verify or expand the search:

Other recruiting trials for Tooth Sensitivity

Currently open trials in the same condition.

NCT07173296 — The Effect of Bleaching Application Mode on Bleaching-induced Tooth Sensitivity. · NA · recruiting

Other University of Campania Luigi Vanvitelli trials

Trials by the same sponsor.

NCT07590349 — Personalized Robotic Telerehabilitation for Upper Limb Functional Recovery After Stroke in a Home-Based Setting · NA · not yet recruiting
NCT06718452 — Tinnitus and Treatment With umPEA-LUT · NA · not yet recruiting
NCT07124676 — Prospective Study Comparing Two Classification Systems for Second-degree Vaginal Tears During Spontaneous Childbirth to · not yet recruiting
NCT07425912 — Real-World Evaluation of TouchCare Nano in Pediatric Type 1 Diabetes · active not recruiting
NCT06991816 — The Brain&Senses Study · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05865275 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Campania Luigi Vanvitelli
Last refreshed: 22 May 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05865275.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing