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Comparative Study Between IVI of Ranibizumab with and Without Prior ACP in Patients with DME Using OCT-A
The goal of this clinical trial is to to evaluate the changes in retinal microvasculature secondary to intra-ocular pressure changes post intra-vitreal injection in patients with diabetic macular oedema highlighting the effect of prior anterior chamber paracentesis on such changes if present . The main question\[s\]it aims to answer are: •\[is there any effect of post intra-vitreal injection IOP spikes on retinal microvasculature?\] •\[is there any effect of Prior Anterior Chamber Paracentesis?\] Participants in group A will be subjected to an identified approved treatment( intra-vitreal injection)\& Participants in group B will be subjected to a prior ACP with the intra-vitreal injection . \]
Details
| Lead sponsor | Ain Shams University |
|---|---|
| Phase | PHASE4 |
| Status | COMPLETED |
| Enrolment | 102 |
| Start date | Sun Jan 01 2023 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Sun Nov 24 2024 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Diabetic Macular Edema
Interventions
- intra-vitreal injection of Ranibizumab
- anterior chamber paracentesis
Countries
Egypt