Who is sponsoring NCT05854875?

NCT05854875 is sponsored by University of Patras.

What drugs are being tested in NCT05854875?

Interventions in NCT05854875: Laparoscopic Roux en Y gastric bypass, Laparoscopic Roux en Y gastric bypass with fundus resection.

What condition does NCT05854875 study?

NCT05854875 studies Type 2 Diabetes, Morbid Obesity, Bariatric Surgery.

Is NCT05854875 still recruiting?

NCT05854875 is currently completed. Last updated 11 May 2023.

Last reviewed 2023-05-11 · How we verify

NCT05854875

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Diabetes Remission After RYGBP and RYGBP With Fundus Resection

Completed NA Last updated 11 May 2023

What this trial tests

NA trial testing Laparoscopic Roux en Y gastric bypass in Type 2 Diabetes in 24 participants. Completed in 10 April 2023.

Timeline

22 September 2019

Primary endpoint
2 March 2023

10 April 2023

Quick facts

Lead sponsor	University of Patras
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	24
Start date	22 September 2019
Primary completion	2 March 2023
Estimated completion	10 April 2023
Sites	1 location across Greece

Drugs / interventions tested

Laparoscopic Roux en Y gastric bypass
Laparoscopic Roux en Y gastric bypass with fundus resection

Conditions studied

Type 2 Diabetes — all drugs for Type 2 Diabetes →
Morbid Obesity — all drugs for Morbid Obesity →
Bariatric Surgery — all drugs for Bariatric Surgery →

Sponsor

University of Patras

Who can join

Adults 18 to 60, any sex, with Type 2 Diabetes or Morbid Obesity. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this randomized clinical trial is to evaluate glycemic control in patients with morbid obesity and type 2 diabetes after Roux-en-Y gastric bypass (RYGBP) and RYGBP with fundus resection. The main questions to answer are: * Rate of diabetes remission and the role of the gastrointestinal hormones * Whether fundus resection leads to improved glycemic control Patients will randomly undergo typical RYGBP or RYGBP with fundus resection. Gastrointestinal hormones profile \[ghrelin, glucagon-like peptide-1 (GLP-1), peptide YY (PYY), glucagon\], glucose levels and insulin response will be measured preoperatively, at 6 months and at 12 months, during 120-min OGTT.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Diabetes Remission After LRYGBP With and Without Fundus Resection: a Randomized Clinical Trial.
Kehagias D, Lampropoulos C, Georgopoulos N, Habeos I, et al · · 2023 · cited 29× · PMID 37783932 · DOI 10.1007/s11695-023-06857-z
Post-Bariatric Hypoglycemia in Individuals with Obesity and Type 2 Diabetes after Laparoscopic Roux-en-Y Gastric Bypass: A Prospective Cohort Study.
Kehagias D, Lampropoulos C, Vamvakas SS, Kehagia E, et al · · 2024 · cited 9× · PMID 39200136 · DOI 10.3390/biomedicines12081671

Verify or expand the search:

Other trials of Laparoscopic Roux en Y gastric bypass

Trials testing the same drug.

NCT02752230 — Comparison of Exparel to Marcaine in Post-Surgical Analgesia in Bariatrics · Phase 4 · withdrawn

Other recruiting trials for Type 2 Diabetes

Currently open trials in the same condition.

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NCT07254689 — The Food for Health Study · NA · recruiting
NCT07558863 — Effect of GLP-1RA on Cardiac Autonomic Neuropathy in Type 2 Diabetes · Phase 4 · recruiting

Other University of Patras trials

Trials by the same sponsor.

NCT07472894 — AI-INFORMED PEER-MENTORING BEHAVIORAL INTERVENTION FOR ANXIETY AND DEPRESSION PRIMARY PREVENTION IN YOUTH · NA · not yet recruiting
NCT07334392 — Impact of a Multicomponent Exercise Program on Cognitive and Functional Outcomes in Patients With Mild Cognitive Impairm · NA · recruiting
NCT07389993 — Diaphragm and Breathing Muscle Characteristics in Women With and Without Diastasis Recti Abdominis After Childbirth · recruiting
NCT06848517 — Synchronous and Asynchronous Telerehabilitation for Women With Urinary Incontinence · NA · recruiting
NCT06161324 — Tele-rehabilitation for Women With Urinary Incontinence · NA · enrolling by invitation

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05854875 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of Patras
Last refreshed: 11 May 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05854875.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing