Last reviewed · How we verify

NCT05853536

In Silico Trials of Surgical Interventions

Status unknown Last updated 10 May 2023
What this trial tests

trial in Cardiovascular Diseases in 13,977,257 participants. Status unknown.

Timeline
1 August 2019
Primary endpoint
1 August 2023
1 August 2024

Quick facts

Lead sponsorUniversity of Leicester
StatusStatus unknown
Study typeOBSERVATIONAL
Enrollment13,977,257
Start date1 August 2019
Primary completion1 August 2023
Estimated completion1 August 2024
Sites1 location across United Kingdom

Conditions studied

Sponsor

University of Leicester

Who can join

18 and older, any sex, with Cardiovascular Diseases. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The project aims to establish a database of cardiovascular patients using HES and linked mortality data. This database will be used to model trials in silico with the aim of informing the design of future cardiovascular trials in the United Kingdom.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Study design for an emulated trial of a 2 arm, parallel, stratified, adaptive, RCT of CABG versus PCI in people requiring myocardial revascularization at high risk (High-Risk REVASC).
    Liao W, Rashid M, Brookes CL, Barber S, et al · · 2026 · PMID 41638385 · DOI 10.1016/j.ahj.2026.107368
  2. Validation of “Days Alive and out of Hospital” as an Outcome Measure After Coronary Artery Bypass Graft Surgery, Acute Coronary Syndrome and Heart Failure Hospitalisation
    Grant R, Liao W, Miksza J, Roman M, et al · · 2024 · DOI 10.1101/2024.02.12.24302587

Verify or expand the search:

Other recruiting trials for Cardiovascular Diseases

Currently open trials in the same condition.

Other University of Leicester trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05853536.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing