Last reviewed · How we verify
NCT05853042: MERITnI
MERITnI - Mindray-hs-cTnI Assay: Analytical and Clinical Evaluation for the Diagnosis and RIsk AssessmenT of Myocardial InfarctIon.
trial testing high-sensitivity cardiac troponin testing in Acute Myocardial Infarction in 1,500 participants. Participants enrolled and being followed up; not accepting new ones.
15 March 2025
Quick facts
| Lead sponsor | Hennepin Healthcare Research Institute |
|---|---|
| Status | Active, enrolled |
| Study type | OBSERVATIONAL |
| Enrollment | 1,500 |
| Start date | 12 December 2022 |
| Primary completion | 15 March 2025 |
| Estimated completion | 15 May 2025 |
| Sites | 1 location across United States |
Drugs / interventions tested
- high-sensitivity cardiac troponin testing
Conditions studied
- Acute Myocardial Infarction — all drugs for Acute Myocardial Infarction →
- Acute Coronary Syndrome — all drugs for Acute Coronary Syndrome →
Sponsor
Hennepin Healthcare Research Institute
Who can join
21 and older, any sex, with Acute Myocardial Infarction or Acute Coronary Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The Mindray High Sensitivity Troponin-I Measurement System is an in vitro diagnostic test for the quantitative determination of high sensitivity cardiac troponin I (hs-cTnI) in human serum or plasma. The Mindray High Sensitivity Troponin-I Measurement System is to be used as an aid in the diagnosis and rule out of acute myocardial infarction (AMI).
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Diagnostic performance of Mindray CL1200i high sensitivity cardiac troponin I assay compared to Abbott Alinity cardiac troponin I assay for the diagnosis of type 1 and 2 acute myocardial infarction in females and males: MERITnI study.
Apple FS, Buda KG, Wagner BP, Sexter A, et al · · 2025 · cited 1× · PMID 39919272 · DOI 10.1515/cclm-2024-1373 -
Symptom Prevalence Among Patients with Serial Troponin Measurements in an Urban Emergency Department
Buda K, Sandoval Y, Smith S, Wagner B, et al · · 2025
Verify or expand the search:
- PubMed search for NCT05853042
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Hennepin Healthcare Research Institute trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05853042 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hennepin Healthcare Research Institute
- Last refreshed: 9 October 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05853042.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing