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NCT05852808: LORAFA
Evaluation of Pain Level Reduction After Low-dose Radiation in Symptomatic Facet Joint Arthritis
NA trial testing Intra-articular steroid injections in Lower Back Pain Chronic in 5 participants. Terminated before completion.
10 May 2024
Quick facts
| Lead sponsor | Silvia Gomez Ordonez |
|---|---|
| Phase | NA |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 5 |
| Start date | 31 October 2023 |
| Primary completion | 10 May 2024 |
| Estimated completion | 10 May 2024 |
| Sites | 1 location across Switzerland |
Drugs / interventions tested
- Intra-articular steroid injections — full drug profile →
- Low-dose radiation therapy
Conditions studied
- Lower Back Pain Chronic — all drugs for Lower Back Pain Chronic →
- Facet Joint Arthrosis — all drugs for Facet Joint Arthrosis →
- Osteoarthritis, Spine — all drugs for Osteoarthritis, Spine →
Sponsor
Silvia Gomez Ordonez — full company profile →
Who can join
45 and older, any sex, with Lower Back Pain Chronic or Facet Joint Arthrosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this clinical trial is to compare low-dose radiation therapy (LDRT) with intra-articular steroid injections in participants suffering from chronic lower back pain as cause of facet joint arthritis (FJA). The main question\[s\] it aims to answer are: * Is LDRT non-inferior to intra-articular steroid injections in terms of pain reduction * Is there a difference in long-term pain reduction between LDRT and intra-articular steroid injections Participants will be randomly assigned to one of the two treatment groups.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Adaptive trials in low back pain and osteoarthritis: How common are they and when should they be used? A systematic review from ClinicalTrials.gov.
Silveira AMC, Wang M, Hall M, Ferreira ML, et al · · 2026 · PMID 42109297 · DOI 10.1016/j.ocarto.2026.100777
Verify or expand the search:
- PubMed search for NCT05852808
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Lower Back Pain Chronic
Currently open trials in the same condition.
- NCT07127380 — Comparison of Clinical Outcomes, Complications Rate and Treatment Costs of Mini-TLIF and MIDLIF in the Treatment of Disc · NA · recruiting
- NCT05657964 — Randomized Trial for cLBP (Gokhale Project) · recruiting
- NCT05801848 — Diagnosis of Bone Metabolism in Patients With Inexplicable Lower Back Pain · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05852808 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Silvia Gomez Ordonez
- Last refreshed: 14 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05852808.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing