NCT05851482 (HRM nomogram) is a NA clinical trial of High resolution manometry in Gastro Esophageal Reflux, sponsored by IRCCS Policlinico S. Donato.

Who is sponsoring NCT05851482?

NCT05851482 is sponsored by IRCCS Policlinico S. Donato.

What drugs are being tested in NCT05851482?

Interventions in NCT05851482: High resolution manometry.

What condition does NCT05851482 study?

NCT05851482 studies Gastro Esophageal Reflux.

Is NCT05851482 still recruiting?

NCT05851482 is currently completed. Last updated 9 May 2023.

Last reviewed 2023-05-09 · How we verify

NCT05851482: HRM nomogram

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Validation of HRM Score for the GERD Diagnosis

Completed NA Last updated 9 May 2023

What this trial tests

NA trial testing High resolution manometry in Gastro Esophageal Reflux in 246 participants. Completed in 29 April 2023.

Timeline

1 December 2022

Primary endpoint
28 February 2023

29 April 2023

Quick facts

Lead sponsor	IRCCS Policlinico S. Donato
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	diagnostic
Enrollment	246
Start date	1 December 2022
Primary completion	28 February 2023
Estimated completion	29 April 2023
Sites	1 location across Italy

Drugs / interventions tested

High resolution manometry

Conditions studied

Gastro Esophageal Reflux — all drugs for Gastro Esophageal Reflux →

Sponsor

IRCCS Policlinico S. Donato

Who can join

Adults 18 to 75, any sex, with Gastro Esophageal Reflux. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this prospective study is to validate a high resolution manometry score to predict pathologic GERD in patients with reflux symptoms. The main question it aims to answer is: Is it possible to predict GERD on high resolution manometry? Participants will be asked to undergo high resolution manometry and pH-study

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The Milan score: A novel manometric tool for a more efficient diagnosis of gastro-esophageal reflux disease.
Siboni S, Sozzi M, Kristo I, Boveri S, et al · · 2024 · cited 28× · PMID 38536701 · DOI 10.1002/ueg2.12565

Verify or expand the search:

Other recruiting trials for Gastro Esophageal Reflux

Currently open trials in the same condition.

NCT07482969 — Prevalence of Symptomatic Gastroesophageal Reflux Disease in Czech Children (Czech GERDKids) · recruiting
NCT05455359 — Gastrointestinal Dysmotility on Aspiration Risk · Phase 4 · recruiting
NCT07131397 — The Effect of Inspiratory Muscle Training in People With Gastroesophageal Reflux Disease · NA · recruiting
NCT06564558 — The Effect of Postural Correction On Gastroesophageal Reflux Disease · NA · recruiting
NCT05570448 — Anti-Reflux Endoscopic TX Using APC (AREA) in GERD Patients: (The AREA Study) · NA · recruiting

Other IRCCS Policlinico S. Donato trials

Trials by the same sponsor.

NCT07295522 — Pharmacological Optimization in Prevention in Heart Failure: A Sex-gap? · Phase 4 · not yet recruiting
NCT07169669 — Multicentre Longitudinal Study of Bone Mineralisation Characteristics in Marfan Syndrome and Ehlers-Danlos Syndrome · not yet recruiting
NCT07455292 — Phenotyping Left Ventricle Failure With Hemodynamic Biomarkers From 4D Flow Magnetic Resonance Imaging · NA · recruiting
NCT07402161 — The Signature of Alzheimer's Disease in Subjective Cognitive Decline · recruiting
NCT06294119 — Multivariate Approach to the Numerical Assessment of Cortical - Autonomic - VAscular Dynamic Interplay · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT05851482 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by IRCCS Policlinico S. Donato
Last refreshed: 9 May 2023

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05851482.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing