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NCT05847530
Pilot Evaluation of the Cynosure Potenza™ System for Treatment of Cosmetic Dermatologic Skin Conditions
NA trial testing Potenza in Wrinkles in 20 participants. Completed in 6 May 2025.
6 May 2025
Quick facts
| Lead sponsor | Cynosure, Inc. |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 20 |
| Start date | 17 August 2023 |
| Primary completion | 6 May 2025 |
| Estimated completion | 6 May 2025 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Potenza
- Icon
Conditions studied
- Wrinkles — all drugs for Wrinkles →
- Scars — all drugs for Scars →
- Stretch Marks — all drugs for Stretch Marks →
- Pigmentation — all drugs for Pigmentation →
Sponsor
Cynosure, Inc. — full company profile →
Who can join
18 and older, any sex, with Wrinkles or Scars. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The primary objective of this pilot study is exploratory investigation evaluating the Potenza microneedle fractional radiofrequency (RF) device and may be used in combination with the Icon intense pulsed light (IPL) device.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
From mechanism to applications: Advanced microneedles for clinical medicine.
Yang Y, Sun H, Sun X, Wang Y, et al · · 2025 · cited 9× · PMID 40463395 · DOI 10.1016/j.bioactmat.2025.04.025
Verify or expand the search:
- PubMed search for NCT05847530
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Potenza
Trials testing the same drug.
- NCT06023303 — Prospective Clinical Study to Assess Safety and to Collect Data on Radiofrequency Microneedling Device(s) For the Purpos · NA · completed
- NCT05097157 — Study To Assess A Radiofrequency Microneedling Device For Dermatologic Conditions · NA · completed
Other recruiting trials for Wrinkles
Currently open trials in the same condition.
- NCT07495865 — Post-market Clinical Follow-up (PMCF) Study of Safety and Performance of 502-01 AnGelHA 2 · recruiting
- NCT07111156 — A Clinical Study to Test the Safety and Effectiveness of Pinorox® for Improving Visible Signs of Facial Aging Such as Wr · NA · active not recruiting
- NCT06724510 — Safety and Efficacy Evaluation of High Intensity Focused Ultrasound Device in Eyebrow Lifting · NA · recruiting
Other Cynosure, Inc. trials
Trials by the same sponsor.
- NCT06023303 — Prospective Clinical Study to Assess Safety and to Collect Data on Radiofrequency Microneedling Device(s) For the Purpos · NA · completed
- NCT05590039 — Study To Evaluate The Safety And Efficacy Of The MyEllevate® Procedure · NA · completed
- NCT05388604 — Clinical Study To Evaluate Paired Treatment With An Alexandrite Laser And Radiofrequency Microneedling For Facial Aging · NA · completed
- NCT05388617 — Study To Assess Radiofrequency Diathermocontraction Device For Muscle Stimulation And The Treatment Of Abdominal Fat · NA · terminated
- NCT05102617 — Post Market Usability Evaluation Of The PicoSure Pro Device · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT05847530 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cynosure, Inc.
- Last refreshed: 28 August 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT05847530.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing